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  1. MUC16 is a heavily glycosylated cell surface mucin cleaved in the tumor microenvironment to shed CA125. CA125 is a serum biomarker expressed by > 95% of non-mucinous advanced stage epithelial ovarian cancers. ...

    Authors: Hsin-Fang Tu, Margaret Wong, Ssu-Hsueh Tseng, Nattha Ingavat, Pola Olczak, Kin Israel Notarte, Chien-fu Hung and Richard B.S. Roden
    Citation: Journal of Ovarian Research 2024 17:19
  2. The ovarian environment of premature ovarian insufficiency (POI) patients exhibits immune dysregulation, which leads to excessive secretion of numerous proinflammatory cytokines that affect ovarian function. A...

    Authors: Bingbing Hu, Xiushuang Zheng and Wei Zhang
    Citation: Journal of Ovarian Research 2024 17:18
  3. Polycystic ovarian syndrome (PCOS) is a genetically complex disorder that involves the interplay of multiple genes and environmental factors. It is characterized by anovulation and irregular menses and is asso...

    Authors: Teodor T. Postolache, Qamar M. Al Tinawi and Claudia Gragnoli
    Citation: Journal of Ovarian Research 2024 17:17
  4. Ovarian cancer (OVCA) is the most lethal gynecologic cancer and chemoresistance remains a major hurdle to successful therapy and survival of OVCA patients. Plasma gelsolin (pGSN) is highly expressed in chemore...

    Authors: Hafiza Bushra Manzoor, Meshach Asare-Werehene, Satyajit Dey Pereira, Kapaettu Satyamoorthy and Benjamin K. Tsang
    Citation: Journal of Ovarian Research 2024 17:15
  5. For women of childbearing age, the biggest problem caused by polycystic ovary syndrome (PCOS) is infertility, which is mainly caused by anovulation, abnormal follicular development, proliferation of small antr...

    Authors: Zichao Huang, Tianyue Xu, Chunling Liu, Honghui Wu, Linglin Weng, Jieyu Cai, Na Liang and Hongshan Ge
    Citation: Journal of Ovarian Research 2024 17:14
  6. Components of the hypothalamic-pituitary axis (HPA) pathway are potential mediators of the genetic risk of polycystic ovarian syndrome (PCOS). Impaired glucocorticoid receptor (NR3C1) expression and function may ...

    Authors: Shumail Syed and Claudia Gragnoli
    Citation: Journal of Ovarian Research 2024 17:13
  7. This study was designed to investigate the pharmacological effects and mechanisms of ErZhiTianGui Decoction (EZTG) for age-related ovarian aging in mice.

    Authors: Jia Zhicheng, Li Yongqian, Wang Peixuan, Yang Kai, Shi Mengyu, Chen Wen, Liang Qihui and Guo Ying
    Citation: Journal of Ovarian Research 2024 17:12
  8. The etiology of polycystic ovary syndrome (PCOS) is complex and variable, and there is no exact cause or good treatment method. Most of the methods of hormones are used to temporarily meet the needs of patient...

    Authors: Shasha Gao, Juan Wang, Lun Wei, Chao Luo, Fei Qian, Le Bo and Caiping Mao
    Citation: Journal of Ovarian Research 2024 17:11
  9. Genetic mosaicism is commonly observed in human blastocysts. Embryos’ morphokinetic feature observed from time-lapse monitoring (TLM) is helpful to predict the embryos’ ploidy status in a non-invasive way. How...

    Authors: Yaoyu Zou, Yilun Sui, Jing Fu, Naidong Ge, Xiaoxi Sun and Yijuan Sun
    Citation: Journal of Ovarian Research 2024 17:10
  10. To investigate the effect of L-carnitine supplementation during the controlled ovarian stimulation (COS) cycle with antagonist protocol in patients with polycystic ovary syndrome (PCOS) diagnosis undergoing IV...

    Authors: Maryam Hafezi, Arezoo Arabipoor, Firouzeh Ghaffari, Samira Vesali, Maryam Zareei and Zahra Hajinaghibali Hessari
    Citation: Journal of Ovarian Research 2024 17:9
  11. Polycystic ovary syndrome (PCOS) is an exceedingly intractable issue affecting female endocrine and reproductive health. However, the etiology and intricate pathological mechanisms of PCOS remain unclear. Nowa...

    Authors: Danni Jiang, Yang Xu, Lin Yang, Pengfei Li, Xiaojuan Han, Qianni Li, Yang Yang and Lan Chao
    Citation: Journal of Ovarian Research 2024 17:7
  12. Polycystic ovarian syndrome (PCOS) is recognized as the most prevalent endocrine disorder among women of reproductive age. While the utilization of assisted reproductive technology (ART) has resulted in favora...

    Authors: Miaomiao Ban, Yifei Sun, Xiaojing Chen, Xiaoqian Zhou, Yiyuan Zhang and Linlin Cui
    Citation: Journal of Ovarian Research 2024 17:6
  13. Existing evidence suggests a relation between cardiovascular dysfunction and diminished ovarian reserve. While it is known that pre-existent cardiovascular dysfunction is also associated with the development o...

    Authors: Bo E. van Bree, Laura M. Jorissen, Désirée A.P.M. Pattinaja, Judith A.P. Bons, Marc E.A. Spaanderman, Olivier Valkenburg and Ron J.T. van Golde
    Citation: Journal of Ovarian Research 2024 17:5
  14. Investigating the utility of serum exosomal markers CA125, HE4, and C5a, both individually and in combination, for distinguishing between benign and malignant ovarian tumors.

    Authors: Huihui Shi, Liya Liu, Xueli Deng, Xiaoyu Xing, Yan Zhang, Yemeli Djouda Rebecca and Liping Han
    Citation: Journal of Ovarian Research 2024 17:4
  15. The intricate interplay of gene expression within ovarian granulosa cells (GCs) is not fully understood. This study aimed to investigate the miRNA regulatory mechanisms of ferroptosis during the process of fol...

    Authors: Gulimire Abudureyimu, Yangsheng Wu, Ying Chen, Liqin Wang, Geng Hao, Jianguo Yu, Jianguo Wang, Jiapeng Lin and Juncheng Huang
    Citation: Journal of Ovarian Research 2024 17:3
  16. The objective of this study was to induce the differentiation of human theca stem cells (hTSCs) into germ cell-like cells (hGCLCs) and assess their developmental progression following in vitro 3D culture with ...

    Authors: Seyedeh Nasim Mirbahari, Christiani A. Amorim, Fatemeh Hassani, Mehdi Totonchi, Mahnaz Haddadi, Mojtaba Rezazadeh valojerdi and Azam Dalman
    Citation: Journal of Ovarian Research 2024 17:2
  17. An unexpected impaired ovarian response pertains to an insufficient reaction to controlled ovarian hyperstimulation. This deficient reaction is identified by a reduced count of mature follicles and retrieved o...

    Authors: Gürkan Uncu, Kiper Aslan, Cihan Cakir, Berrin Avci, Isil Kasapoglu and Carlo Alviggi
    Citation: Journal of Ovarian Research 2024 17:1
  18. Epithelial ovarian cancer (OC) is the fourth leading cause of cancer-related deaths in women, with a 5-year survival rate of 30%-50%. Platinum resistance is the chief culprit for the high recurrence and mortal...

    Authors: Mengjun Zhang, Jialin Wang, Yan Guo, Haodi Yue and Lindong Zhang
    Citation: Journal of Ovarian Research 2023 16:240
  19. Polycystic ovary syndrome (PCOS) is a widespread heterogeneous disease that is in association with genetic, epigenetic, endocrine and environmental factors. Adipose-derived mesenchymal stem cell (ASC) and ASC-...

    Authors: Golnaz Shafiei, Mona Saheli, Sepideh Ganjalikhan-hakemi, Tahereh Haghpanah and Seyed Noureddin Nematollahi-mahani
    Citation: Journal of Ovarian Research 2023 16:238
  20. As a novel prognostic and inflammatory marker, the systemic immune-inflammation index (SII) has come to the foreground in recent years. SII may be used as an indicator reflecting the progressive inflammatory p...

    Authors: Xin Li, Ting Luan, Yi Wei, Juan Zhang, JuanJuan Zhang, Chun Zhao and Xiufeng Ling
    Citation: Journal of Ovarian Research 2023 16:236
  21. To investigate the efficacy of fertility-preserving treatment for young women with synchronous primary neoplasm of endometrium and ovary.

    Authors: Qujia Gama, Shuhan Luo, Pengfei Wu, Lulu Wang, Sijia Liu, Hongwei Zhang, Li Sun, Yiqin Wang, Min Yu, Xiaojun Chen, Weiwei Shan and Xuezhen Luo
    Citation: Journal of Ovarian Research 2023 16:235
  22. The ovary is an important reproductive organ in mammals, and its development directly affects the sexual maturity and reproductive capacity of individuals. MicroRNAs (miRNAs) are recognized as regulators of re...

    Authors: Yanyan Wang, Jianmin Wang, Qing Li, Rong Xuan, Yanfei Guo, Peipei He and Tianle Chao
    Citation: Journal of Ovarian Research 2023 16:234
  23. Chromobox protein homolog 7 (CBX7), a member of the Polycomb repressor complex, is a potent epigenetic regulator and gene silencer. Our group has previously reported that CBX7 functions as a tumor suppressor i...

    Authors: Yi Zhang, Roslyn Tedja, Michael Millman, Terrence Wong, Alexandra Fox, Hussein Chehade, Meyer Gershater, Nicholas Adzibolosu, Radhika Gogoi, Matthew Anderson, Thomas Rutherford, Zhenggang Zhang, Michael Chopp, Gil Mor and Ayesha B. Alvero
    Citation: Journal of Ovarian Research 2023 16:233
  24. The epithelial-mesenchymal transition (EMT) promotes cell signaling and morphology alterations, contributing to cancer progression. Exosomes, extracellular vesicles containing proteins involved in cell-cell co...

    Authors: Germano Aguiar Ferreira, Carolina Hassibe Thomé, Clarice Izumi, Mariana Lopes Grassi, Guilherme Pauperio Lanfredi, Marcus Smolka, Vitor Marcel Faça and Francisco José Candido dos Reis
    Citation: Journal of Ovarian Research 2023 16:232
  25. Clinical trials are currently exploring combinations of PARP inhibitors and immunotherapies for the treatment of ovarian cancer, but their effects on the ovarian tumour microenvironment (TME) remain unclear. H...

    Authors: Salar Farokhi Boroujeni, Galaxia Rodriguez, Kristianne Galpin, Edward Yakubovich, Humaira Murshed, Dalia Ibrahim, Sara Asif and Barbara C. Vanderhyden
    Citation: Journal of Ovarian Research 2023 16:231
  26. Clinical prediction models play an important role in the field of medicine. These can help predict the probability of an individual suffering from disease, complications, and treatment outcomes by applying spe...

    Authors: Guan Guixue, Pu Yifu, Gao Yuan, Liu Xialei, Shi Fan, Sun Qian, Xu Jinjin, Zhang Linna, Zhang Xiaozuo, Feng Wen and Yang Wen
    Citation: Journal of Ovarian Research 2023 16:230
  27. Inflammation and immunity are two main characteristics of tumor microenvironment (TME). Interferon-gamma (IFN-γ) is generally considered as a pro-inflammatory cytokine which mediates anti-tumor immune response...

    Authors: Hui Zheng, Xiaolin Guan, Xin Meng, Ying Tong, Yanchun Wang, Suhong Xie, Lin Guo and Renquan Lu
    Citation: Journal of Ovarian Research 2023 16:229
  28. The genotype-phenotype relationships between TUBB8 variants and female infertility are difficult to clearly define due to the complex inheritance patterns and the highly heterogeneous phenotypes. This study aims ...

    Authors: Tingwenyi Hu, Chong Li, Sen Qiao, Weiwei Liu, Wei Han, Wei Li, Rong Shi, Xia Xue, Juanzi Shi, Guoning Huang and Tingting Lin
    Citation: Journal of Ovarian Research 2023 16:228
  29. Existing studies have investigated the relationship between the levels of serum inhibin B (INHB), anti-müllerian hormone (AMH) and precocious puberty in girls, but the results are inconsistent.

    Authors: Mei Jiang, Ying Gao, Tiange Qu, Yuechen Ji, Yiwen Niu, Jiaxin Zhang and Ling Huang
    Citation: Journal of Ovarian Research 2023 16:227
  30. The rescue in vitro mature(Rescue IVM) technique allows the use of immature oocytes collected in conventional COH to obtain more mature oocytes for fertilization through in vitro maturation. Some studies have ...

    Authors: Jianbo Wei, Zhongyu Luo, Xiyuan Dong, Huizi Jin, Lixia Zhu and Jihui Ai
    Citation: Journal of Ovarian Research 2023 16:226
  31. The oocyte and its surrounding cumulus cells (CCs) exist as an inseparable entity. The maturation of the oocyte relies on communication between the oocyte and the surrounding CCs. However, oocyte evaluation is...

    Authors: Yena Hu, Ran Zhang, Shuoping Zhang, Yaxing Ji, Qinwei Zhou, Lizhi Leng, Fei Meng, Fei Gong, Guangxiu Lu, Ge Lin and Liang Hu
    Citation: Journal of Ovarian Research 2023 16:225
  32. The influence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on assisted reproductive technology (ART) has received increasing attention. It has been reported that the SARS-CoV-2 Rib...

    Authors: Yuling Mao, Yachao Yao, Hongzi Du, Zheng Wang, Xueliang Zhou, Ming Zeng, Chunyan Wang, Hanyan Liu, Yang Luo, Honghai Hong, Jianqiao Liu and Lei Li
    Citation: Journal of Ovarian Research 2023 16:224
  33. Ovarian cancer is a significant public health concern with a poor prognosis for epithelial ovarian cancer. To explore the potential of immunotherapy in treating epithelial ovarian cancer, we investigated the i...

    Authors: Hua Yang, Xiangyu Gu, Rong Fan, Qun Zhu, Sen Zhong, Xirun Wan, Qian Chen, Lan Zhu and Fengzhi Feng
    Citation: Journal of Ovarian Research 2023 16:223
  34. The objective of this study is to investigate the effects of an ethanolic extract derived from Agaricus subrufescens on rat models exhibiting Polycystic Ovarian Syndrome (PCOS) induced by Letrozole.

    Authors: Sarad Pawar Naik Bukke, Bharghava Bhushan Rao Pathange, Srikanth Kumar Karumanchi, Jalaiah Marri, Revathi Boyina, Kavya Rachamsetty, Bhargavi Manchikalapati, Saidi Odoma and Bello Hussaini
    Citation: Journal of Ovarian Research 2023 16:221
  35. High-grade serous ovarian cancer (OvCa) is the most common type of epithelial OvCa. It is usually diagnosed in advanced stages, leaving a woman’s chance of survival below 50%. Despite traditional chemotherapeu...

    Authors: Melayshia McFadden, Santosh Kumar Singh, Briana Kinnel, Sooryanarayana Varambally and Rajesh Singh
    Citation: Journal of Ovarian Research 2023 16:220
  36. Angiogenesis and metastasis contributes substantially to the poor outcome of patients with ovarian cancer. We aimed to explore the role and mechanisms of the long non-coding RNA NEAT1 (nuclear enriched abundan...

    Authors: Yang Liu, Yan Li, Yanzhi Wu, Yiyue Zhao, Xi Hu and Chunyi Sun
    Citation: Journal of Ovarian Research 2023 16:219
  37. High-grade serous carcinoma (HGSC) is the most common and aggressive subtype of epithelial ovarian cancer, characterized by gain-of-function TP53 mutations originating in the fallopian tube epithelium. Therapeuti...

    Authors: Madison Pereira, Alice Glogova, Jacob Haagsma, Julia Stewart, Trevor G. Shepherd and Jim Petrik
    Citation: Journal of Ovarian Research 2023 16:218
  38. Authors: Xing‑Hua Pan, Xue‑Juan Zhang, Xiang Yao, Ni‑Ni Tian, Zai‑Ling Yang, Kai Wang, Xiang‑Qing Zhu, Jing Zhao, Jie He, Xue‑Min Cai, Rong‑Qing Pang and Guang‑Ping Ruan
    Citation: Journal of Ovarian Research 2023 16:217

    The original article was published in Journal of Ovarian Research 2021 14:133

  39. Women with polycystic ovary syndrome (PCOS) have higher intestinal mucosal permeability, leading to the lipopolysaccharide (LPS) leakage and endotoxemia. This, in turn, leads to oxidative stress (OS) and neuro...

    Authors: Negin Nikrad, Mahdieh Abbasalizad Farhangi, Fatemeh Pourteymour Fard Tabrizi, Maryam Vaezi, Ata Mahmoudpour and Mehran Mesgari-Abbasi
    Citation: Journal of Ovarian Research 2023 16:216
  40. Polycystic ovary syndrome (PCOS) is an endocrine disorder characterized by ovarian cysts, high androgen levels, and irregular menstruation. The causality between PCOS and breast cancer (BC) has been widely dis...

    Authors: Runxiang Cao, Lanlan Chen, Yutong Liu, Xuyutian Wang, Ruolin Ma, Qian Zhao and Ye Du
    Citation: Journal of Ovarian Research 2023 16:215
  41. No residual disease (CC 0) following cytoreductive surgery is pivotal for the prognosis of women with advanced stage epithelial ovarian cancer (EOC). Improving CC 0 resection rates without increasing morbidity...

    Authors: Diederick de Jong, Amudha Thangavelu, Timothy Broadhead, Inga Chen, Dermot Burke, Richard Hutson, Racheal Johnson, Angelika Kaufmann, Peter Lodge, David Nugent, Aaron Quyn, Georgios Theophilou and Alexandros Laios
    Citation: Journal of Ovarian Research 2023 16:214
  42. The oocyte cumulus complex is mainly composed of an oocyte, the perivitelline space, zona pellucida and numerous granulosa cells. The cumulus granulosa cells (cGCs) provide a particularly important microenviro...

    Authors: Chongyi Shu, Yiqi Yu, Xiaopan Chen, Jiansheng Guo, Yier Zhou, Dandan Wu, Tianyun Yang, Yuhang Fan, Qiongxiao Huang and Jing Shu
    Citation: Journal of Ovarian Research 2023 16:213
  43. To study whether CAG repeat polymorphism of androgen receptor (AR) contributes to the risk of polycystic ovarian morphology (PCOM) with antral follicle count (AFC) ≥ 20 in the context of new international guideli...

    Authors: Xueqi Yan, Xueying Gao, Qian Shang, Ziyi Yang, Yuteng Wang, Li Liu, Wei Liu, Dan Liu, Fang Cheng, Shigang Zhao, Han Zhao, Junli Zhao and Zi-Jiang Chen
    Citation: Journal of Ovarian Research 2023 16:211
  44. Premature ovarian insufficiency (POI) is a highly heterogeneous disease, and up to 25% of the cases can be explained by genetic causes. G protein-coupled receptor 3 (GPR3) plays an important role in oocyte arr...

    Authors: Shuting Ren, Feng Zhang, Lingyue Shang, Xi Yang, Yuncheng Pan, Xiaojin Zhang and Yanhua Wu
    Citation: Journal of Ovarian Research 2023 16:210

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