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Table 1 Genes with differential (2.0 ± 0.1-fold; p < 0.05) ovarian expression in 180-day LY mice compared to age-matched black mice.

From: Progressive obesity leads to altered ovarian gene expression in the Lethal Yellow mouse: a microarray study

Accession Number

Relative Expression

Name

NM_028744.1

0.4

phosphatidylinositol 4-kinase type 2 beta

AK041828.1

0.4

SH3-domain kinase binding protein 1

NM_023130.1

0.5

hnRNP-associated with lethal yellow ( Raly )

NM_018867.3

0.5

carboxypeptidase × 2 (M14 family)

NM_008289.1

0.5

hydroxysteroid 11-beta dehydrogenase 2 (Hsd11b2)

AW411692.1

0.55

BCL2-like 11 (apoptosis facilitator)

NM_010350.1

0.55

glutamate receptor, ionotropic, NMDA2C (epsilon 3)

NM_007428.2

0.55

angiotensinogen

NM_009338.1

1.9

acetyl-CoA-acetyl transferase

NM_145942.2

1.9

3-hydroxy-3-methylglutaryl-CoenzymeA-synthase (Hmgcs1)

BI246566.1

1.9

hepatic lipase

NM_026784.1

1.9

phosphomevalonate kinase

BM945729.1

1.9

NAD(P) dependent steroid dehydrogenase-like

NM_011485.3

1.9

steroidogenic acute regulatory protein (Star)

NM_053245.1

1.9

aryl hydrocarbon receptor-interacting protein-like 1

NM_030210.1

2

acetoacetyl-CoA synthetase

NM_008288.1

2

hydroxysteroid 11-beta dehydrogenase 1 (Hsd11b1)

NM_025436.1

2

sterol-C4-methyl oxidase-like (Sc4mol)

BY616448.1

2.1

fibroblast growth factor 12

NM_138656.1

2.1

mevalonate (diphospho) decarboxylase (Mvd)

NM_146006.1

2.2

lanosterol synthase

NM_010742.1

2.3

lymphocyte antigen 6 complex, locus D

NM_009714.1

2.4

asialoglycoprotein receptor 1 (Asgr1)

NM_020010.1

2.5

cytochrome P450, 51 (Cyp51)

NM_145360.1

2.6

isopentenyl-diphosphate delta isomerase (Idd1)

NM_009731.1

5.6

aldo-keto reductase family 1, member B7 (Akr1b7)

NM_008493.3

6.5

leptin

NM_015770.2

350

agouti

  1. Genes structurally associated with the LY mutation are shown in bold. N = 3 animals per group.