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Table 1 Clinical, hormonal and metabolic data of PCOS treated patients (anovulatory and ovulatory groups) and PCOS untreated controls (control group) at baseline and at six-month follow-up.

From: Does metformin affect ovarian morphology in patients with polycystic ovary syndrome? A retrospective cross-sectional preliminary analysis

Group Anovulatory PCOS (n. 10) Ovulatory PCOS (n.10) Control (n. 10)
  Baseline Six months Baseline Six months Baseline Six months
Age (years) 28.20 ± 3.45 28.20 ± 3.42 28.10 ± 3.31 28.10 ± 3.33 28.40 ± 3.43 28.40 ± 3.43
BMI (Kg/m2) 22.92 ± 1.51 23.84 ± 1.46 22.93 ± 1.71 22.81 ± 2.08 22.99 ± 1.71 23.13 ± 1.98
WHR 0.85 ± 0.11 0.83 ± 0.14 0.84 ± 0.13 0.84 ± 0.12 0.86 ± 0.10 0.86 ± 0.16
Ferriman-Gallwey score 12.70 ± 2.41 12.70 ± 2.26 12.13 ± 2.34 11.81 ± 2.48 12.68 ± 2.53 12.54 ± 1.94
FSH (mIU/mL) 5.83 ± 1.40 5.82 ± 1.25 5.78 ± 1.51 5.68 ± 1.52 5.63 ± 1.70 5.62 ± 1.27
LH (mIU/mL) 12.65 ± 3.51 12.14 ± 1.52 11.73 ± 3.64 11.58 ± 3.56 12.90 ± 4.15 12.30 ± 3.00
TSH (μU/mL) 3.10 ± 0.73 3.14 ± 0.49 2.97 ± 0.83 2.99 ± 0.62 3.0 ± 0.68 3.00 ± 0.52
PRL (ng/mL) 9.52 ± 1.81 10.02 ± 1.97 9.12 ± 2.31 8.99 ± 2.23 9.89 ± 2.02 10.09 ± 1.32
E2(pg/mL) 48.80 ± 14.95 48.18 ± 14.90 52.28 ± 17.02 53.93 ± 13.39 51.77 ± 9.10 52.55 ± 14.60
P (ng/mL) 1.27 ± 0.45 1.26 ± 0.31 1.39 ± 0.42 1.29 ± 0.62 1.43 ± 0.36 1.46 ± 0.34
17-OHP (μg/L) 1.74 ± 0.50 1.59 ± 0.82 1.54 ± 0.53 1.50 ± 0.63 1.84 ± 0.50 1.93 ± 0.71
T (ng/mL) 4.70 ± 1.23 4.55 ± 1.11* 5.01 ± 1.64 3.41 ± 0.98* 5.15 ± 1.58 5.20 ± 0.78
A (ng/mL) 4.59 ± 1.99 4.34 ± 1.80* 5.16 ± 1.74 3.23 ± 1.07^ 4.97 ± 1.36 4.75 ± 0.99
DHEAS (ng/mL) 2690.01 ± 195.67 2653.48 ± 126.05 2685.72 ± 204.65 2557.25 ± 437.86 2511.82 ± 242.16 2483.07 ± 562.54
SHBG (nmol/L) 31.4 ± 1.78 35.90 ± 1.66*° 32.40 ± 3.86 42.82 ± 2.39^ 32.10 ± 2.51 33.64 ± 2.45
FAI (%) 15.06 ± 4.35 14.37 ± 4.15* 14.97 ± 4.39 10.44 ± 3.01^ 13.60 ± 3.39 12.94 ± 3.19
Fasting glucose (mmol/L) 4.72 ± 0.45 4.79 ± 0.33 4.65 ± 0.50 5.03 ± 0.98 4.73 ± 0.38 4.84 ± 0.43
Fasting insulin (μU/mL) 16.24 ± 3.60 14.94 ± 2.36*° 15.63 ± 4.94 12.98 ± 1.53* 17.92 ± 4.35 12.27 ± 0.84
GIR (mg/10-4 U) 5.59 ± 1.16 6.53 ± 1.00*° 5.96 ± 1.62 7.38 ± 1.14* 5.32 ± 1.39 5.45 ± 0.92
HOMA 3.32 ± 0.61 3.02 ± 0.46*° 3.10 ± 0.62 2.61 ± 0.39* 3.51 ± 0.66 3.47 ± 0.25
  1. * P < 0.05 vs. baseline; ^ P < 0.001 vs. baseline; ° P < 0.05 vs. ovulatory PCOS group.