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Table 1 Clinical, hormonal and metabolic data of PCOS treated patients (anovulatory and ovulatory groups) and PCOS untreated controls (control group) at baseline and at six-month follow-up.

From: Does metformin affect ovarian morphology in patients with polycystic ovary syndrome? A retrospective cross-sectional preliminary analysis

Group

Anovulatory PCOS (n. 10)

Ovulatory PCOS (n.10)

Control (n. 10)

 

Baseline

Six months

Baseline

Six months

Baseline

Six months

Age (years)

28.20 ± 3.45

28.20 ± 3.42

28.10 ± 3.31

28.10 ± 3.33

28.40 ± 3.43

28.40 ± 3.43

BMI (Kg/m2)

22.92 ± 1.51

23.84 ± 1.46

22.93 ± 1.71

22.81 ± 2.08

22.99 ± 1.71

23.13 ± 1.98

WHR

0.85 ± 0.11

0.83 ± 0.14

0.84 ± 0.13

0.84 ± 0.12

0.86 ± 0.10

0.86 ± 0.16

Ferriman-Gallwey score

12.70 ± 2.41

12.70 ± 2.26

12.13 ± 2.34

11.81 ± 2.48

12.68 ± 2.53

12.54 ± 1.94

FSH (mIU/mL)

5.83 ± 1.40

5.82 ± 1.25

5.78 ± 1.51

5.68 ± 1.52

5.63 ± 1.70

5.62 ± 1.27

LH (mIU/mL)

12.65 ± 3.51

12.14 ± 1.52

11.73 ± 3.64

11.58 ± 3.56

12.90 ± 4.15

12.30 ± 3.00

TSH (μU/mL)

3.10 ± 0.73

3.14 ± 0.49

2.97 ± 0.83

2.99 ± 0.62

3.0 ± 0.68

3.00 ± 0.52

PRL (ng/mL)

9.52 ± 1.81

10.02 ± 1.97

9.12 ± 2.31

8.99 ± 2.23

9.89 ± 2.02

10.09 ± 1.32

E2(pg/mL)

48.80 ± 14.95

48.18 ± 14.90

52.28 ± 17.02

53.93 ± 13.39

51.77 ± 9.10

52.55 ± 14.60

P (ng/mL)

1.27 ± 0.45

1.26 ± 0.31

1.39 ± 0.42

1.29 ± 0.62

1.43 ± 0.36

1.46 ± 0.34

17-OHP (μg/L)

1.74 ± 0.50

1.59 ± 0.82

1.54 ± 0.53

1.50 ± 0.63

1.84 ± 0.50

1.93 ± 0.71

T (ng/mL)

4.70 ± 1.23

4.55 ± 1.11*

5.01 ± 1.64

3.41 ± 0.98*

5.15 ± 1.58

5.20 ± 0.78

A (ng/mL)

4.59 ± 1.99

4.34 ± 1.80*

5.16 ± 1.74

3.23 ± 1.07^

4.97 ± 1.36

4.75 ± 0.99

DHEAS (ng/mL)

2690.01 ± 195.67

2653.48 ± 126.05

2685.72 ± 204.65

2557.25 ± 437.86

2511.82 ± 242.16

2483.07 ± 562.54

SHBG (nmol/L)

31.4 ± 1.78

35.90 ± 1.66*°

32.40 ± 3.86

42.82 ± 2.39^

32.10 ± 2.51

33.64 ± 2.45

FAI (%)

15.06 ± 4.35

14.37 ± 4.15*

14.97 ± 4.39

10.44 ± 3.01^

13.60 ± 3.39

12.94 ± 3.19

Fasting glucose (mmol/L)

4.72 ± 0.45

4.79 ± 0.33

4.65 ± 0.50

5.03 ± 0.98

4.73 ± 0.38

4.84 ± 0.43

Fasting insulin (μU/mL)

16.24 ± 3.60

14.94 ± 2.36*°

15.63 ± 4.94

12.98 ± 1.53*

17.92 ± 4.35

12.27 ± 0.84

GIR (mg/10-4 U)

5.59 ± 1.16

6.53 ± 1.00*°

5.96 ± 1.62

7.38 ± 1.14*

5.32 ± 1.39

5.45 ± 0.92

HOMA

3.32 ± 0.61

3.02 ± 0.46*°

3.10 ± 0.62

2.61 ± 0.39*

3.51 ± 0.66

3.47 ± 0.25

  1. * P < 0.05 vs. baseline; ^ P < 0.001 vs. baseline; ° P < 0.05 vs. ovulatory PCOS group.
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Journal of Ovarian Research

ISSN: 1757-2215

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