Figure 4
From: Targeting of mesenchymal stem cells to ovarian tumors via an artificial receptor
MSC-AR increase binding to erbB2-expressing ovarian tumors. (A) Overexpression of erbB2 in SKOV3ip ovarian tumor xenografts was confirmed by erbB2 staining (a-erbB2 staining, b-negative control). B) MSC-GFP and MSC-AR labeled with firefly luciferase were injected ip in SCID mice bearing SKOV3ip1 ovarian tumor xenografts at 2x106 cell/mouse. Tumors were collected after 24 hrs and luciferase expression was measured in luciferase analysis. Data are presented as MSC numbers per mg protein in tumor homogenates.