Figure 7

Orthotopic tumor growth in Tg MISIIR-TAg-Low mice monitored and quantified in vivo by BLI. SCID and TgMISIIR-TAg-EE7 mice were given unilateral or bilateral intrabursal injections with 2 × 10⁵ MOVCAR 5009 or 5447 cells and subjected to weekly bioluminescent imaging to monitor tumor growth. A) Quantitative analysis of total photon counts from dorsal images of TgMISIIR-TAg-EE7 mice injected i.b. with MOVCAR 5009 cells (mice 7245 and 7263) and MOVCAR 5447 cells (mice 7244 and 7261). B) Dorsal images of control SCID and TgMISIIR-TAg-EE7 mice injected i.b. with MOVCAR 5009 cells (mice 7245 and 7263) and MOVCAR 5447 cells (mice 7244 and 7261) showing proscribed luminescent signals at the site of unilateral (mice 7245 and 7244) or bilateral (mice 7263 and 7261) i.b. injection.