Development of a syngeneic mouse model of epithelial ovarian cancer

Quinn, Bridget A; Xiao, Fang; Bickel, Laura; Martin, Lainie; Hua, Xiang; Klein-Szanto, Andres; Connolly, Denise C

doi:10.1186/1757-2215-3-24

Journal of Ovarian Research

Table 1 Growth of MOVCAR cells in C57BL/6 and SCID mice

From: Development of a syngeneic mouse model of epithelial ovarian cancer

Host	MOVCAR cell line	# cells injected i.p.	Survival (days post tumor cell injection)	Tumor location	Ascites (>1.0 mL)
C57BL/6	12	1 × 10⁷	243	None
C57BL/6	12	1 × 10⁷	256	None
C57BL/6	12	1 × 10⁷	256	None
C57BL/6	12	1 × 10⁷	256	None
C57BL/6	12	2 × 10⁷	326	None
C57BL/6	12	2 × 10⁷	326	None
C57BL/6	12	3 × 10⁷	208	None
C57BL/6	12	3 × 10⁷	208	None
C57BL/6	12	3 × 10⁷	303	None
C57BL/6	12	3 × 10⁷	303	None
SCID	12	1 × 10⁷	93	Peritoneal cavity, invasion of ovarian cortex	+
SCID	12	1 × 10⁷	100	Peritoneal cavity, invasion of ovarian cortex	+
SCID	12	1 × 10⁷	103	Peritoneal cavity, invasion of ovarian cortex	+
SCID	12	1 × 10⁷	103	Peritoneal cavity, invasion of ovarian cortex	+
SCID	12	1 × 10⁷	105	Peritoneal cavity, invasion of ovarian cortex	+
SCID	5009	1 × 10⁷	25	Peritoneal cavity	+
SCID	5009	1 × 10⁷	25	Peritoneal cavity	+
SCID	5009	1 × 10⁷	34	Peritoneal cavity	+
SCID	5009	1 × 10⁷	34	Peritoneal cavity	+
SCID	5009	1 × 10⁷	34	Peritoneal cavity	+
SCID	5009	1 × 10⁷	34	Peritoneal cavity	+
SCID	5183	1 × 10⁷	109	Peritoneal cavity, invasion of ovarian cortex	+
SCID	5183	1 × 10⁷	116	Peritoneal cavity, invasion of ovarian cortex
SCID	5183	1 × 10⁷	116	Peritoneal cavity, invasion of ovarian cortex
SCID	5348	1 × 10⁷	141	Peritoneal cavity	+
SCID	5348	1 × 10⁷	141	Peritoneal cavity, invasion of ovarian cortex	+
SCID	5348	5 × 10⁶	141	Peritoneal cavity	+
SCID	5447	1 × 10⁷	95	Peritoneal cavity, invasion of ovarian cortex	+
SCID	5447	1 × 10⁷	95	Peritoneal cavity, invasion of ovarian cortex	+
SCID	5447	5 × 10⁶	95	Peritoneal cavity
SCID	5447	5 × 10⁶	97	Peritoneal cavity, invasion of ovarian cortex	+
SCID	5612	1 × 10⁷	74	Peritoneal cavity, invasion of ovarian cortex
SCID	5612	5 × 10⁶	97	Peritoneal cavity	+

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ISSN: 1757-2215

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