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Figure 1 | Journal of Ovarian Research

Figure 1

From: Microarray analysis of Foxl2 mediated gene regulation in the mouse ovary derived KK1 granulosa cell line: Over-expression of Foxl2 leads to activation of the gonadotropin releasing hormone receptor gene promoter

Figure 1

Comparison of differential gene expression in KK1 cells to mouse ovary developmental stages. Genesifter software was used to determine differentially expressed genes in KK1 cells and mouse in vivo samples [7]. The KK1 analysis for differentially expressed genes generated a cumulative listing of 2520 differentially expressed genes among the mock, VP16, and mad transfected cell groups combined (Additional file 5). The mouse samples compared wild type to knockout for each stage as follows: E13, 3289 genes (Additional file 6); E16, 2995 genes (Additional file 7); and P0, 4330 genes (Additional file 8). Comparisons between groups of genes were performed with Genesifter Intersector. The comparisons are represented by circles and are as follows: KK1 vs. E16; KK1 vs. E13; and KK1 vs. P0. The number of genes in each grouping corresponding to color codes is indicated on the right. A listing of all genes may be found in Additional file 9.

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