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Table 1 Gene Regulation

From: Microarray analysis of Foxl2 mediated gene regulation in the mouse ovary derived KK1 granulosa cell line: Over-expression of Foxl2 leads to activation of the gonadotropin releasing hormone receptor gene promoter

Gene
Symbol
Name Entrez
Gene ID
Group
Bcl11a** B cell CLL/lymphoma 11a (zinc finger protein) 14025 MA -4.5
Bub3 Budding uninhibited by benzimidazoles 3 homolog 12237 E16
Cdc25a Cell division cycle 25 homolog A (S. pombe) 12530 P0
Dazl deleted in azoospermia-like 13164 MA -3.1
Etv1 Ets variant gene 1 14009 RA+6.5, E16
Gabpa GA repeat binding protein, alpha 14390 P0
Greb1 Growth regulation by estrogen in breast cancer 1 268527 E13, E16
Hoxb5** Homeo box B5 15413 RA-5.1, E16
Id4 Inhibitor of DNA binding 4 15904 MA -5.6
Mcm7 Minichromosome maintenance deficient 7 17220 E16, P0
Nr4a2 Nuclear receptor subfamily 4, group A, member 2 18227 E16
Plagl1 pleiomorphic adenoma gene-like 1 22634 MA +5.3
Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 20720 MR +2.4
Snw1 SNW domain containing 1 66354 E16, P0
Sox21* SRY-box containing gene 21 223227 MR +2.5
Zfp106 zinc finger protein 106 20402 MR +5.1
  1. All genes listed that do not have an asterisk after the gene symbol are common to our study and the in vivo in mouse ovary study only [7]. Genes denoted by a single asterisk* are common to our study and the human KGN cell line only [6]. Those indicated by ** are common to all three studies. The (-) symbol indicates fold decreased expression. The (+) symbol indicates fold increased expression. MA compares mock (M) transfected cells to activated (A) cells (Foxl2-VP16 transfected). MR compares mock (M) transfected to repressed (R) cells (Foxl2-Mad transfected). RA compares repressed to activated cells. E16 and E13 are mouse embryonic stages day 16 and 13, respectively. P0 is mouse birth stage.