Figure 1
From: Trastuzumab Sensitizes Ovarian Cancer Cells to EGFR-targeted Therapeutics
Selection of HER2 positive ovarian carcinoma-derived cell lines. Cell lysates, normalized for protein content, were probed following SDS-PAGE with anti-HER2 and anti-EGFR antibody. A1847 and IGROV-1 cells, which express moderate levels of HER2, and OVCAR-7 and SKOV-3, which express high levels of HER2, were selected for further study. Cell lines selected for further study are noted with an asterisk. Tubulin expression is included as a loading control. These blots are representative of two successive passages of ovarian carcinoma-derived cell lines.