Identification and characterization of a spontaneous ovarian carcinoma in Lewis rats

Table 1 Survival after intraperitoneal injection of FNAR cells.

Survival Following Tumor Challenge
No. of Cells Injected	No. of Animals	Survival - Days (No. of Animals)
5 × 10⁴	N = 6	175 (6)
1 × 10⁵	N = 8	150 (4) 155 (3), 160 (1)
5 × 10⁵	N = 6	155 (2), 160 (4)
1 × 10⁶	N = 6	150 (5), 152 (1)

The survival time of rats corresponds to the number of FNAR cells injected intraperitoneally. Animals were observed daily for general health and abdominal extension. The animals were sacrificed upon becoming moribund, which was characterized by extreme lethargy, paleness, and abdominal extension. The abdominal cavity was examined histologically for the presence of tumor cells in the peritoneal fluid and for tumor masses attached to the visceral organs and the abdominal wall.

ISSN: 1757-2215