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Figure 4 | Journal of Ovarian Research

Figure 4

From: The hen model of human ovarian cancer develops anti-mesothelin autoantibodies in response to mesothelin expressing tumors

Figure 4

Immunohistochemical localization of mesothelin in normal hen ovaries and hen ovaries containing tumor. Staining was not observed in normal ovaries (A-C) in either the stromal or follicular (F) compartments or in ovarian tumors that did not express mesothelin (D-F). Mesothelin staining was observed in the ovarian surface epithelium (SE) and clusters of cells in the ovarian stroma (ST) of tumors that express mesothelin (G-I). Examples of different ovarian tumor histology are shown (D and F, advanced mucinous tumor; E, advanced endometrioid tumor; G and H, advanced serous and endometrioid mixed tumor respectively; I, advanced serous tumor). The original magnification was 40×.

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