Figure 4
From: MicroRNA signature of cis-platin resistant vs. cis-platin sensitive ovarian cancer cell lines
Quantitative real-time PCR (qRT-PCR) analysis of differentially expressed miRNAs in A2780 vs. A2780/CP70 ovarian cancer cell lines. Cells were harvested for total RNA and subjected to cDNA synthesis. Expression levels of 5 miRNAs were analyzed by qRT-PCR. The bars represents normalized % change values with mean ± SD (n = 3) between A2780 and A2780/CP70. *represents significant at p-value (≤ 0.05). The data presented showed that miRNAs hsa-miR-193b and hsa-miR-642 were upregulated 64% and 22% respectively, whereas hsa-miR-625, hsa-miR-20b, and hsa-let-7c were down regulated 22%, 44% and 18% respectively in A2780/CP70 cells as compared to A2780 cells.