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Table 1 Pathways affected by the putative targets of miR-625

From: MicroRNA signature of cis-platin resistant vs. cis-platin sensitive ovarian cancer cell lines

KEGG Pathway

Gene Name

Found Genes

-ln(p-value)

KEGG Pathway ID

Ubiquitin mediated proteolysis

UBE2NL, UBE2N, FBXW7, SIAH1

4

12.75

hsa04120

p53 signaling pathway

SIAH1, IGF1

2

4.77

hsa04115

Regulation of autophagy

ATG5

1

1.62

hsa04140

Focal adhesion

COL1A1, IGF1

2

1.27

hsa04510

Neurodegenerative Diseases

FBXW7

1

1.16

hsa01510

Lysine degradation

SETD1A

1

1.16

hsa00310

mTOR signaling pathway

IGF1

1

0.9

hsa04150

Glioma

IGF1

1

0.59

hsa05214

Glycerophospholipid metabolism

ACHE

1

0.55

hsa00564

Renal cell carcinoma

ARNT

1

0.52

hsa05211

Melanoma

IGF1

1

0.49

hsa05218

Long-term depression

IGF1

1

0.46

hsa04730

ECM-receptor interaction

COL1A1

1

0.4

hsa04512

Hematopoietic cell lineage

CSF3R

1

0.39

hsa04640

Neuroactive ligand-receptor interaction

GHRHR

1

0.37

hsa04080

Cytokine-cytokine receptor interaction

CSF3R

1

0.37

hsa04060

Prostate cancer

IGF1

1

0.32

hsa05215

TGF-beta signaling pathway

FST

1

0.31

hsa04350

Axon guidance

SEMA6C

1

0.1

hsa04360

Cell Communication

COL1A1

1

0.04

hsa01430

Jak-STAT signaling pathway

CSF3R

1

0.01

hsa04630

Wnt signaling pathway

SIAH1

1

0

hsa04310