Figure 1

Comparison of GPX3 levels of healthy female controls vs. women with serous ovarian cancer for women of all ages: Figure 1A shows a group-wise comparison of GPX3 in healthy female controls vs. women diagnosed with papillary serous ovarian cancer while Figure 1B shows a stage-wise comparison of GPX3 in healthy female controls vs. women diagnosed with papillary serous ovarian cancer. Star (*) denotes statistically significant decrease in GPX3 expression when compared to controls. Hash (#) denotes statistically significant difference in GPX3 expression when compared to early stage samples. Women diagnosed with serous ovarian cancer show a statistically significant decrease in the levels of GPX3. A stage-wise examination shows that there is a significant decrease in GPX3 levels in late stage and recurrent cancer. There is also a significant difference in levels of GPX3 between patients with early and late stage/recurrent disease.