Skip to main content

Table 4 GPX3 associations with cancer

From: Decreased levels of serum glutathione peroxidase 3 are associated with papillary serous ovarian cancer and disease progression

Cancer Type

Overexpression/

Downregulation

RNA/

Protein

Cell/Tissue/

Serum/Plasma

Species

References

Esophageal Squamous Cell

Downregulation

mRNA, protein

Tumor tissue

Human

[31]

Gastric, Cervical, Thyroid, Head, Neck, Lung and Melanoma

Downregulation

mRNA, protein

Tumor tissue

Human

[32]

Thyroid

Downregulation

mRNA

Tumor tissue

Human

[33]

Ovarian Clear Cell

Upregulation

mRNA

Cell Lines

Human

[25]

Ovarian Clear Cell

Upregulation

mRNA, protein

Tumor tissue

Human

[24]

Ovarian Clear Cell

Upregulation

mRNA

Tumor tissue

Human

[26]

Ovarian Papillary Serous: Late Stage/previously treated

Presence

Protein

Ascites Fluid

Human

[27]

Glioblastoma

Downregulation

mRNA, protein

Tumor tissue, Serum

Human

[20]

Meningioma

Downregulation

mRNA

Tumor Tissue

Human

[34]

Lung

Downregulation

protein

Whole blood, Plasma (activity measurement)

Human

[35]

Endometrial adenocarcinoma

Downregulation

mRNA

Tumor Tissue

Human, Rat

[19]

Barrett's adenocarcinoma

Downregulation

mRNA

Tumor Tissue

Human

[36]

Prostate

Downregulation

mRNA

Tumor tissue

Human

[23]

Lung

Upregulation

protein

Blood serum

Mouse

[37]

Prostate cancer

Upregulation

protein

Blood serum

Human, Rat

[38]