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Figure 1 | Journal of Ovarian Research

Figure 1

From: Thailandepsins are new small molecule class I HDAC inhibitors with potent cytotoxic activity in ovarian cancer cells: a preclinical study of epigenetic ovarian cancer therapy

Figure 1

Chemical structure of HDAC inhibitors. Thailandepsin A (TDP-A), thailandepsin B (TDP-B) and FK228 are depsipeptides characterized by a bicyclic structure containing a signature disulfide bond; the prodrugs can be activated by cellular reduction, indicated by a star sign (*). SAHA is a hydroxamic acid marked by a pound sign (#)

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