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Table 2 Minimum effective concentration (MEC)

From: Are platinum agents, paclitaxel and irinotecan effective for clear cell carcinoma of the ovary? DNA damage detected with γH2AX induced by anticancer agents

 

Cmax

MEC

PTX

10 μg/ml

50 ng/ml

CDDP

7 μg/ml

1 μg/ml

CBDCA

55 μg/ml

10 μg/ml

SN-38

30 μg/ml

1 ng/ml

  1. Cmax; clinical maximum drug concentration.