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Table 1 List of 136 CSC-inhibitory compounds identified by HTS (%growth ≤ 50%, p-adj. ≤ 0.1) compared to GI 50 of OVCAR-3 cells

From: Identification of inhibitors of ovarian cancer stem-like cells by high-throughput screening

NSC %growth SD p-value p-adj (Holms) GI 50(-log 10) OVCAR-3
618332 3.3 4.0 3.73E-07 2.78E-04 5.08
219734 4.2 2.0 9.47E-07 6.88E-04 6.43
128305 4.9 3.4 8.02E-06 5.59E-03 4.34
168597 5.1 5.5 2.42E-06 1.73E-03 7.69
328426 5.3 3.2 4.64E-07 3.44E-04 7.62
143648 5.6 2.3 1.64E-07 1.23E-04 7.43
165563 6.1 4.4 3.58E-07 2.67E-04 8.05
145366 7.1 2.1 5.21E-08 4.00E-05 5.75
636132 7.3 3.2 9.47E-07 6.89E-04 4.00
323241 7.7 2.4 1.59E-07 1.20E-04 7.54
622732 8.0 4.9 4.93E-06 3.46E-03 4.90
208913 8.0 3.5 8.17E-07 5.96E-04 3.80
306864 8.0 3.1 3.86E-07 2.88E-04 5.76
4320 8.0 3.3 6.94E-08 5.31E-05 9.56
3053 8.4 3.9 1.38E-08 1.07E-05 8.54
265450 8.5 3.2 8.14E-08 6.21E-05 7.20
354844 8.6 6.0 4.34E-07 3.22E-04 7.26
164914 8.8 3.7 2.95E-09 2.32E-06 6.75
63701 8.9 3.4 1.00E-09 7.88E-07 7.46
697726 9.0 3.5 5.32E-09 4.16E-06 7.56
637578 9.1 2.3 1.04E-07 7.87E-05 8.36
614928 9.3 2.0 7.60E-07 5.56E-04 4.51
667467 9.8 3.9 3.53E-10 2.79E-07 4.00
65937 10.2 2.1 1.08E-07 8.16E-05 -
65423 10.4 3.1 2.61E-10 2.06E-07 5.78
690634 10.8 2.9 7.52E-07 5.51E-04 7.59
24559 10.8 3.6 9.91E-11 7.86E-08 7.35
18268 10.9 3.4 2.24E-08 1.73E-05 8.41
243023 11.0 3.4 4.48E-06 3.15E-03 8.07
635448 11.1 5.9 1.19E-08 9.27E-06 7.69
7525 11.3 2.4 4.99E-06 3.49E-03 7.60
616232 11.6 4.0 3.97E-10 3.13E-07 4.00
269754 11.9 8.4 1.62E-04 1.03E-01 8.10
680506 12.4 5.0 4.85E-07 3.58E-04 -
58514 12.5 3.1 1.34E-08 1.04E-05 9.52
353527 12.8 4.1 7.25E-07 5.32E-04 7.77
106408 12.8 2.4 1.29E-06 9.30E-04 7.34
620358 13.0 5.5 1.37E-05 9.27E-03 5.72
65104 13.2 4.3 9.57E-07 6.95E-04 8.76
325319 13.2 2.7 7.94E-07 5.80E-04 8.23
328166 13.4 5.4 4.72E-07 3.49E-04 7.35
658144 13.4 2.6 1.51E-08 1.17E-05 6.68
260610 13.9 5.5 2.48E-06 1.77E-03 6.79
631529 14.5 3.2 4.08E-07 3.04E-04 5.82
85236 14.5 2.5 8.67E-08 6.61E-05 5.82
376265 14.7 7.5 1.41E-05 9.53E-03 8.50
349644 14.9 4.6 2.95E-05 1.95E-02 7.72
89671 15.0 2.5 6.73E-07 4.95E-04 7.55
105808 15.3 3.8 1.15E-05 7.87E-03 5.96
635121 16.0 5.3 9.44E-06 6.53E-03 5.52
93419 17.1 7.4 2.92E-05 1.93E-02 6.13
268251 17.4 6.2 2.99E-06 2.12E-03 8.96
202000 17.7 5.0 3.03E-09 2.38E-06 4.05
659999 18.0 6.4 1.30E-08 1.01E-05 5.99
172924 18.5 3.1 7.81E-08 5.97E-05 6.67
673622 18.5 9.1 1.83E-05 1.23E-02 6.59
146604 19.2 4.6 2.41E-09 1.90E-06 6.65
349156 19.5 2.6 1.73E-06 1.24E-03 6.92
526417 19.7 3.8 5.38E-08 4.13E-05 9.28
400978 20.3 2.4 7.26E-09 5.67E-06 7.97
24817 20.4 5.8 2.23E-08 1.72E-05 7.67
319726 20.6 4.0 5.30E-09 4.15E-06 8.00
614826 20.8 5.2 1.41E-05 9.52E-03 6.66
679524 20.9 3.5 1.94E-10 1.54E-07 7.50
629301 20.9 5.5 2.23E-05 1.49E-02 4.80
129414 21.1 7.4 5.48E-05 3.58E-02 7.41
337766 21.4 5.8 1.20E-08 9.34E-06 6.73
7532 21.7 8.3 3.12E-06 2.21E-03 8.00
172946 21.7 5.6 1.25E-05 8.50E-03 7.46
328587 22.1 4.6 2.91E-09 2.29E-06 5.77
34391 22.2 4.2 4.20E-07 3.12E-04 5.60
153858 22.5 4.8 9.62E-07 6.97E-04 9.48
625483 22.8 9.7 2.53E-05 1.68E-02 4.66
82116 23.0 5.7 1.02E-07 7.75E-05 -
72961 23.1 4.4 1.27E-07 9.59E-05 5.60
65380 23.6 6.9 9.38E-05 6.03E-02 7.20
85700 23.7 4.7 1.18E-08 9.20E-06 5.98
336628 23.7 5.9 2.62E-07 1.97E-04 4.77
345647 23.8 48.5 1.03E-05 7.09E-03 6.59
102811 23.9 5.3 1.99E-08 1.54E-05 6.96
669356 24.5 8.1 2.09E-06 1.49E-03 8.00
7521 24.5 6.9 9.49E-05 6.08E-02 7.52
352876 24.7 6.7 4.35E-05 2.86E-02 6.27
148958 24.9 6.9 1.03E-07 7.81E-05 3.09
613009 25.0 5.7 3.89E-06 2.75E-03 7.41
10447 25.5 6.6 3.49E-07 2.61E-04 4.65
301460 25.6 5.0 2.20E-06 1.57E-03 8.00
605756 25.8 6.4 6.31E-07 4.65E-04 5.68
407806 26.5 3.1 1.95E-06 1.40E-03 7.44
67574 27.0 6.0 1.21E-06 8.74E-04 7.68
700582 27.2 5.8 1.02E-07 7.74E-05 6.57
304421 27.9 4.2 4.98E-06 3.49E-03 6.47
521777 28.1 6.1 3.29E-08 2.53E-05 8.00
330500 29.0 4.8 6.10E-07 4.50E-04 6.05
255109 29.6 4.9 1.15E-05 7.84E-03 7.02
302979 30.4 10.8 5.65E-05 3.68E-02 5.43
33410 30.8 5.6 6.80E-08 5.21E-05 7.98
693632 30.8 7.4 2.11E-07 1.58E-04 6.44
24818 31.0 5.3 9.92E-06 6.85E-03 8.12
24819 31.1 4.7 1.14E-06 8.25E-04 8.47
52141 31.3 6.0 1.14E-06 8.24E-04 7.14
96932 31.4 6.9 6.94E-07 5.10E-04 6.77
349155 31.7 7.1 1.99E-05 1.33E-02 6.45
97911 32.4 7.6 6.23E-05 4.05E-02 5.70
243928 32.5 9.0 8.80E-06 6.11E-03 5.69
83265 34.8 6.7 4.05E-06 2.86E-03 5.70
637993 34.8 9.9 8.30E-05 5.36E-02 5.50
145669 34.9 6.6 3.26E-07 2.44E-04 7.75
157930 34.9 6.5 5.26E-06 3.68E-03 6.16
132791 35.2 15.3 1.52E-04 9.67E-02 6.96
331757 35.6 15.4 1.55E-04 9.84E-02 5.11
269142 36.0 10.3 9.02E-06 6.25E-03 6.68
1906 36.2 3.5 4.46E-08 3.43E-05 4.15
14229 37.6 6.1 9.93E-08 7.56E-05 5.55
1620 37.7 8.4 4.88E-06 3.43E-03 4.00
622627 38.4 11.4 1.82E-05 1.22E-02 5.28
215989 38.6 7.1 2.91E-06 2.07E-03 -
13973 40.2 5.5 1.38E-06 9.94E-04 6.28
332598 40.6 7.4 2.18E-05 1.45E-02 10.38
126727 41.3 11.0 6.20E-05 4.04E-02 -
248436 41.4 9.5 1.35E-05 9.15E-03 4.08
705330 41.6 10.5 1.35E-05 9.17E-03 5.70
166454 41.9 7.2 8.76E-07 6.39E-04 5.41
84074 42.9 7.3 1.84E-05 1.23E-02 5.46
632841 43.2 6.1 1.47E-06 1.06E-03 5.83
116693 43.6 5.1 1.86E-07 1.40E-04 5.50
375575 44.8 5.1 1.04E-05 7.14E-03 5.71
98904 45.5 11.5 1.23E-04 7.85E-02 6.05
629971 46.5 10.7 1.01E-05 6.96E-03 6.54
403883 48.3 7.0 2.37E-05 1.57E-02 4.00
267033 48.5 10.9 4.31E-05 2.84E-02 6.35
36437 48.5 5.5 8.51E-06 5.91E-03 5.23
49842 49.1 10.6 2.34E-05 1.56E-02 9.71
654259 49.8 9.0 2.57E-06 1.83E-03 7.23
182986 50.1 9.1 1.52E-05 1.02E-02 5.27
93739 50.4 6.5 1.54E-05 1.04E-02 5.40