Table 3 Compounds preferentially inhibitory for CSC
From: Identification of inhibitors of ovarian cancer stem-like cells by high-throughput screening
NSC | Name | % growth | SD | p-adj |
|---|---|---|---|---|
618332 | 2,3-Dibromonaphthoquinone | 3.3 | 4.0 | 2.78E-04 |
128305 | 5,7-Dihydroxy-3',4'-dimethoxyflavone | 4.9 | 3.4 | 5.59E-03 |
636132 | 3-Cyano-N,3-bis(2-methylphenyl)-2-oxopropanamide | 7.3 | 3.2 | 6.89E-04 |
622732 | N-(4-chlorophenyl)-1-methyl-1H-pyrazolo[3,4-b]quinolin-5-amine | 8.0 | 4.9 | 3.46E-03 |
208913 | Ethyl 2-(((1-adamantyl(methyl)amino) carbonyl)amino)propanoate | 8.0 | 3.5 | 5.96E-04 |
614928 | 3,3,4,4-Tetramethyltetrahydro-2,5-furandiol | 9.3 | 2.0 | 5.56E-04 |
667467 | 2-Phenyl-1,4-thiazino[3,2-c]quinoline-3-thione | 9.8 | 3.9 | 2.79E-07 |
616232 | Dibromodulcitol | 11.6 | 4.0 | 3.13E-07 |
635121 | N'-(1-(4H-1,4-benzothiazin-2-yl)ethylidene)-2-hydroxybenzohydrazide | 16.0 | 5.3 | 6.53E-03 |
202000 | (4Z)-4-[(3,4-dichlorophenyl) methylidene]-2-(furan-2-yl)-1,3-oxazol-5-one | 17.7 | 5.0 | 2.38E-06 |
629301 | 3,6-Dihydro-3,6-ethanocyclohepta[cd] [1]benzofuran-10,10,11,11-tetracarbonitrile | 20.9 | 5.5 | 1.49E-02 |
34391 | Cryptocyanine iodide | 22.2 | 4.2 | 3.12E-04 |
625483 | 1-(2-Chloro-6-fluorophenyl)-1H,3H-Thiazolo(3,4-a)benzimidazole | 22.8 | 9.7 | 1.68E-02 |
72961 | 8-Azaadenosine | 23.1 | 4.4 | 9.59E-05 |
336628 | Merbarone | 23.7 | 5.9 | 1.97E-04 |
148958 | Ftorafur | 24.9 | 6.9 | 7.81E-05 |
10447 | Purpurin | 25.5 | 6.6 | 2.61E-04 |
302979 | Shikoccin | 30.4 | 10.8 | 3.68E-02 |
637993 | 6H-Imidazo[4,5,1-de]acridin-6-one, 5-[2-(diethylamino) ethylamino]-8-methox`y-1-methyl-, dihydrochloride | 34.8 | 9.9 | 5.36E-02 |
331757 | 2-Anthracenecarboxamide, N-[4-(diethylamino)-1-methylbutyl]-9,10-dihydro-9,10-dioxo-, monohydrochloride | 35.6 | 15.4 | 9.84E-02 |
1906 | Piperidinium piperidinedithiocarbamate | 36.2 | 3.5 | 3.43E-05 |
14229 | Mepacrine | 37.6 | 6.1 | 7.56E-05 |
1620 | 4-[[(2-furanyl)methyl]amino]-1H-pyrazolo[3,4-D]pyrimidine | 37.7 | 8.4 | 3.43E-03 |
622627 | 2-(chloromethyl)-1,3-dinitro-5-(trifluoromethyl)benzene | 38.4 | 11.4 | 1.22E-02 |
248436 | Platinum, dibromo(6-thioguanosine-N7,S6)-, (SP-4-3)- | 41.4 | 9.5 | 9.15E-03 |
166454 | Decamine | 41.9 | 7.2 | 6.39E-04 |
84074 | Phosphonium, (3-bromopropyl)triphenyl- bromide | 42.9 | 7.3 | 1.23E-02 |
116693 | 2,3-bis(benzoyloxy)succinic acid compound with 1,4-dimethyl-2-((4-methylphenyl)(phenyl)-l 4-sulfanyl)benzene (1:1) | 43.6 | 5.1 | 1.40E-04 |
403883 | Cedran-8-ol | 48.3 | 7.0 | 1.57E-02 |
36437 | Crassin acetate | 48.5 | 5.5 | 5.91E-03 |
182986 | Diaziquone | 50.1 | 9.1 | 1.02E-02 |
93739 | Fuchsine | 50.4 | 6.5 | 1.04E-02 |