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Table 3 Compounds preferentially inhibitory for CSC

From: Identification of inhibitors of ovarian cancer stem-like cells by high-throughput screening

NSC Name % growth SD p-adj
618332 2,3-Dibromonaphthoquinone 3.3 4.0 2.78E-04
128305 5,7-Dihydroxy-3',4'-dimethoxyflavone 4.9 3.4 5.59E-03
636132 3-Cyano-N,3-bis(2-methylphenyl)-2-oxopropanamide 7.3 3.2 6.89E-04
622732 N-(4-chlorophenyl)-1-methyl-1H-pyrazolo[3,4-b]quinolin-5-amine 8.0 4.9 3.46E-03
208913 Ethyl 2-(((1-adamantyl(methyl)amino) carbonyl)amino)propanoate 8.0 3.5 5.96E-04
614928 3,3,4,4-Tetramethyltetrahydro-2,5-furandiol 9.3 2.0 5.56E-04
667467 2-Phenyl-1,4-thiazino[3,2-c]quinoline-3-thione 9.8 3.9 2.79E-07
616232 Dibromodulcitol 11.6 4.0 3.13E-07
635121 N'-(1-(4H-1,4-benzothiazin-2-yl)ethylidene)-2-hydroxybenzohydrazide 16.0 5.3 6.53E-03
202000 (4Z)-4-[(3,4-dichlorophenyl) methylidene]-2-(furan-2-yl)-1,3-oxazol-5-one 17.7 5.0 2.38E-06
629301 3,6-Dihydro-3,6-ethanocyclohepta[cd] [1]benzofuran-10,10,11,11-tetracarbonitrile 20.9 5.5 1.49E-02
34391 Cryptocyanine iodide 22.2 4.2 3.12E-04
625483 1-(2-Chloro-6-fluorophenyl)-1H,3H-Thiazolo(3,4-a)benzimidazole 22.8 9.7 1.68E-02
72961 8-Azaadenosine 23.1 4.4 9.59E-05
336628 Merbarone 23.7 5.9 1.97E-04
148958 Ftorafur 24.9 6.9 7.81E-05
10447 Purpurin 25.5 6.6 2.61E-04
302979 Shikoccin 30.4 10.8 3.68E-02
637993 6H-Imidazo[4,5,1-de]acridin-6-one, 5-[2-(diethylamino) ethylamino]-8-methox`y-1-methyl-, dihydrochloride 34.8 9.9 5.36E-02
331757 2-Anthracenecarboxamide, N-[4-(diethylamino)-1-methylbutyl]-9,10-dihydro-9,10-dioxo-, monohydrochloride 35.6 15.4 9.84E-02
1906 Piperidinium piperidinedithiocarbamate 36.2 3.5 3.43E-05
14229 Mepacrine 37.6 6.1 7.56E-05
1620 4-[[(2-furanyl)methyl]amino]-1H-pyrazolo[3,4-D]pyrimidine 37.7 8.4 3.43E-03
622627 2-(chloromethyl)-1,3-dinitro-5-(trifluoromethyl)benzene 38.4 11.4 1.22E-02
248436 Platinum, dibromo(6-thioguanosine-N7,S6)-, (SP-4-3)- 41.4 9.5 9.15E-03
166454 Decamine 41.9 7.2 6.39E-04
84074 Phosphonium, (3-bromopropyl)triphenyl- bromide 42.9 7.3 1.23E-02
116693 2,3-bis(benzoyloxy)succinic acid compound with 1,4-dimethyl-2-((4-methylphenyl)(phenyl)-l 4-sulfanyl)benzene (1:1) 43.6 5.1 1.40E-04
403883 Cedran-8-ol 48.3 7.0 1.57E-02
36437 Crassin acetate 48.5 5.5 5.91E-03
182986 Diaziquone 50.1 9.1 1.02E-02
93739 Fuchsine 50.4 6.5 1.04E-02