Figure 4
Silencing and/or blocking of CD151 impedes SKOV3 and OVCAR5 migration and invasion. A-C) CD151 knockdown with siCD151 transfection at the mRNA (a) and protein (b-c) levels. d) Reduction of SKOV3 and OVCAR5 migration through transwell membranes in response to either siCD151 transfection or αCD151 antibody treatment. e) Reduction of SKOV3 and OVCAR5 invasion through matrigel and transwell membranes in response to either siCD151 transfection or treatment with αCD151 antibody. *p < 0.01. Results are representative of 3 separate experiments performed in triplicate.