Cell line | Gene designation | Protein name | General function | Fold change | P value for fold change | Fluorescence value resistant line | Fluorescence value parent line |
---|---|---|---|---|---|---|---|
A2780CBN | AKR1C3 | Aldo-keto reductase family 1 member C3 | Catalyzes the conversion of aldehydes and ketones to alcohols | −3.07 | 4.94 x 10-3 | 18.75 | 56.25 |
 | ANXA1 | Annexin A1 | Calcium dependent phospholipid binding protein | −104.15 | 1.38 x 10-4 | 96.50 | 9992.50 |
 | CDH7 | Cadherin 7 | Cell to cell adhesion glycoprotein | 2.08 | 1.29 x 10-4 | 67.25 | 32.75 |
 | GCLC | Glutamate-cysteine ligase catalytic subunit | Rate limiting enzyme of glutathione synthesis | 8.50 | 5.85 x 10-5 | 6907.25 | 815.00 |
 | GSTO1 | Glutathione S-transferase omega 1 | Stress response protein, catalyzes addition of glutathione to toxic substrates | 2.38 | 1.07 x 10-3 | 23166.50 | 9726.50 |
 | MT2A | Metallothionein 2A | Heavy metal binding protein | 3.69 | 4.15 x 10-6 | 4899.50 | 1266.00 |
 | PARP9 | Poly(ADP)-ribose polymerase family, member 9 | Catalyzes addition of ADP-ribose moieties to substrate proteins | 9.40 | 1.95 x 10-3 | 2523.25 | 275.25 |
A2780DXL | CYP1B1 | Cytochrome P450 family 1, subfamily B, polypeptide 1 | Phase 1 enzyme in drug metabolism | −37.77 | 2.00 x 10-8 | 491.50 | 14858.38 |
 | LGI1 | Leucine-rich glioma inactivated 1 | Metastasis regulator | 175.85 | 1.03 x 10-9 | 5449.25 | 30.00 |
 | ABCB1 | ATP-binding cassette transport subfamily B, member 1 | Multidrug transporter (MDR/TAP family) | 33.62 | 8.22 x 10-11 | 21065.40 | 649.60 |
 | ABCB4 | ATP-binding cassette transport subfamily B, member 4 | Multidrug transporter (MDR/TAP family) | 141.27 | 5.88 x 10-10 | 11876.75 | 84.63 |
A2780CBNDXL | ABCB1 | ATP-binding cassette transport subfamily B, member 1 | Multidrug transporter (MDR/TAP family) | 35.28 | 2.43E-03 | 474.25 | 13.00 |
 | ABCB4 | ATP-binding cassette transport subfamily B, member 4 | Multidrug transporter (MDR/TAP family) | 22.70 | 1.89x10-03 | 108.75 | 5.00 |
 | AKR1C3 | Aldo-keto reductase family 1 member C3 | Catalyzes the conversion of aldehydes and ketones to alcohols | 7.30 | 2.62 x 10-3 | 400.75 | 55.75 |
 | FLRT3 | Fibronectin Leucine-rich Repeat Transmembrane protein 3 | Helps regulate cadherin mediated cell adhesion and cell morphogenesis | −115.40 | 1.79 x 10-3 | 39.50 | 4423.25 |
 | GSTO2 | Glutathione S-transferase 2 | Stress response protein, catalyzes addition of glutathione to toxic substrates | 5.34 | 2.68 x 10-4 | 2133.25 | 400.00 |
 | CDH7 | Cadherin 7 | Cell to cell adhesion glycoprotein | 68.82 | 9.24 x 10-4 | 5223.75 | 75.70 |
 | CDH11 | Cadherin 11 | Cell to cell adhesion glycoprotein | 1022.24 | 1.57 x 10-4 | 10708.75 | 10.50 |