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Table 3 Validation gene set, genes present in all three cell lines according to microarray analysis

From: Distinct genetic alterations occur in ovarian tumor cells selected for combined resistance to carboplatin and docetaxel

Gene designation Protein name General function Cell line Fold change P value for fold change Fluorescence value resistant line Fluorescence value parent line
LAYN Layilin Binds hyaluronan, may play a role in cell adhesion and motility A2780CBN −154.83 5.63 x 10-4 88.25 13106.25
    A2780DXL −12.95 4.64 x 10-10 75.00 948.50
    A2780CBNDXL −145.93 8.16 x 10-4 151.75 14364.25
PRSS7 TMPRSS15, Transmembrane protease, serine 15/enterokinase Membrane bound enterokinase A2780CBN 164.34 9.35 x 10-3 1927.75 15.50
    A2780DXL 84.44 2.24 x 10-8 3028.75 37.63
    A2780CBNDXL 123.06 1.79 x 10-3 6559.00 60.00