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Table 4 Comparison of gene expression fold changes by microarray and Q-PCR

From: Distinct genetic alterations occur in ovarian tumor cells selected for combined resistance to carboplatin and docetaxel

Gene

A2780CBN

A2780DXL

A2780CBNDXL

 

Microarray

Q-PCR

Microarray

Q-PCR

Microarray

Q-PCR

ABCB1

NS

NS

33.62

73753.41

35.28

2198.19

ABCB4

NS

NS

141.27

3617.62

22.70

224.52

AKR1C3

−3.07

−6.30

NS

NS

7.30

16.37

ANXA1

−104.15

−154.12

NS

8.53

NS

−6.44

CDH7

5.21

NS

NS

NS

68.82

329.30

CDH11

NS

NS

NS

12.10

1022.24

761.14

CYP1B1

NS

NS

−37.77

−517.88

NS

3.57

FLRT3

NS

−342.64

NS

−933.12

−115.40

−101.97

GCLC

11.45

9.98

NS

NS

NS

NS

GSTO1

2.38

NS

NS

NS

NS

NS

GSTO2

NS

NS

NS

9.13

5.34

10.06

LAYN

−154.83

−7275.97

−12.95

−12945.21

−11.03

−1214.05

LGI1

NS

−0.64

175.85

143.67

NS

NS

MT2A

3.87

NS

NS

2.86

NS

NS

PARP9

9.40

2.10

NS

2.95

NS

18.46

PRSS7

164.34

160.48

84.44

487.41

123.06

802.50

  1. NS = not significantly different between parent and resistant line.