Adrenocortical steroid response to ACTH in different phenotypes of non-obese polycystic ovary syndrome

Table 1 Baseline clinical and hormonal characteristics of the women with PCOS, women with H only and control groups

Parameters	PCOS	H	Control	P
Parameters	(n = 119)	(n = 24)	(n = 39)	(overall)
Age (year)	22.2 ± 4.1	23.8 ± 4.9	24.4 ± 2.9	NS
BMI (kg/m²)	22.5 ± 3.1	22.1 ± 2.3	21.2 ± 2.08	NS
WHR	0.76 ± 0.06	0.77 ± 0.04	0.75 ± 0.06	NS
mFG	8.7 ± 5.3ª	10.0 ± 3.4ª	0.6 ± 0.9	<0.001
Testosterone (ng/dl)	70.4 ± 34.5ª	70.3 ± 30.7ª	34.9 ± 11.6	<0.001
SHBG (nmol/l)	39.6 ± 20.7ª	32.8 ± 16.7ª	56.5 ± 29.1	<0.001
FAI	8.8 ± 7.6ª	8.5 ± 4.5ª	2.7 ± 1.6	<0.001
DHEAS (μg/dl)	278 ±134^b	314 ± 115ª	204 ± 74	<0.001
FPG (mg/dl)	82.4 ± 11.8	81.2 ± 10.7	83.7 ± 11.2	NS
Fasting insulin (μIU/ml)	11.1 ± 5.9	9.2 ± 3.5	9.4 ± 3.1	NS
HOMA-IR	2.3 ± 1.3	1.8 ± 0.7	1.9 ± 0.7	NS

Results are expressed as mean ± SD. NS not significant, BMI body mass index, WHR waist-to-hip ratio, mFG modified Ferriman-Gallwey score, SHBG sex hormone-binding globulin, FAI free androgen index, DHEAS dehydroepiandrosterone sulfate, FPG fasting plasma glucose, HOMA-IR homeostatic model assesment of insulin resistance.
^a P <0.001 vs. Control.
^b P <0.01 vs. Control.

ISSN: 1757-2215