Adrenocortical steroid response to ACTH in different phenotypes of non-obese polycystic ovary syndrome

Table 3 Comparisons of clinical and hormonal characteristics among different phenotypes of PCOS

Parameters	PHO	OH	PH	PO	P
Parameters	(n = 50)	(n = 32)	(n = 23)	(n = 14)	(overall)
Age (year)	22.4 ± 4.5	22.4 ± 4.3	22.3 ± 3.3	20.8 ± 3.4	NS
BMI (kg/m²)	22.6 ± 3.1	22.7 ± 3.2	22.1 ± 2.9	22.5 ± 4.04	NS
WHR	0.78 ± 0.05	0.77 ± 0.05	0.75 ± 0.06	0.77 ± 0.07	NS
mFG	8.2 ± 5.0^a,*	10.9 ± 5.1^a	10.6 ± 3.6^a	1.4 ± 1.7	<0.001
Testosterone (ng/dl)	74.8 ± 37.6^a	77.9 ± 30.8^a	71.7 ± 29.1^a	35.9 ± 15.7	<0.001
SHBG (nmol/l)	39.9 ± 23.5	36.9 ± 17.8	38.6 ± 20.7	46.0 ± 15.7	NS
FAI	9.9 ± 8.4^a	9.6 ± 8.0^a	8.8 ± 5.8^b	2.8 ± 1.4	<0.01
DHEAS (μg/dl)	277 ± 127 ^b	312 ±140^b	294 ± 136^b	174.9 ± 95.8	<0.01
FPG (mg/dl)	82.0 ± 12.6	81.4 ± 11.5	83.1 ± 9.3	84.9 ± 14.4	NS
Fasting insulin (μIU/ml)	12.3 ± 7.5^c	11.2 ± 3.7^c	8.2 ± 4.1	10.2 ± 4.9	<0.01
HOMA-IR	2.6 ± 1.6^c	2.3 ± 0.8^c	1.7 ± 0.9	2.3 ± 1.2	<0.05

Results are expressed as mean ± SD. NS not significant, PHO polycystic ovaries, oligo-anovulation and hyperandrogenism, OH oligo-anovulation and hyperandrogenism, PH polycystic ovaries and hyperandrogenism, PO polycystic ovaries and oligo-anovulation, BMI body mass index, WHR waist-to-hip ratio, mFG modified Ferriman-Gallwey score, SHBG sex hormone-binding globulin, FAI free androgen index, DHEAS dehydroepiandrosterone sulfate, FPG fasting plasma glucose, HOMA-IR homeostatic model assesment of insulin resistance.
^a P <0.001 vs. PO.
^b P <0.01 vs. PO.
^c P <0.01 vs. PH.
*P =0.05 vs. OH.

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