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Table 1 Associations between DACH2 expression and clinicopathological parameters in all patients and patients with serous carcinoma.

From: Discovery of dachshund 2 protein as a novel biomarker of poor prognosis in epithelial ovarian cancer

 

All

Serous carcinoma

Factor

DACH2

DACH2

Age

  

R

0.044

0.078

p

0.603

0.483

n

143

84

Differentiation grade

  

R

-0,031

-0.189

p

0.716

0.086

n

143

84

Clinical stage

  

R

0.025

0.078

p

0.779

0.494

n

131

80

Ki67

  

R

0.208

0.086

p

0.013*

0.435

n

141

84

AR

  

R

0.028

-0.045

p

0.738

0.683

n

143

84

ER

  

R

0.122

-0.067

p

0.151

0.554

n

139

81

PR

  

R

0.130

0.085

p

0.126

0.437

n

141

85

RBM3

  

R

-0,072

-0.167

p

0.393

0.129

n

141

84

Chek1

  

R

0.194

0.139

p

0.024*

0.225

n

134

78

Chek2

  

R

0.182

0.155

p

0.032*

0.164

n

139

78

MCM3

  

R

0.252

0.104

p

0.003**

0.360

n

134

79

  1. R = Spearman's correlation coefficient, p = p-value, n = number of cases available for analysis. ER = estrogen receptor, PR = progesterone receptor, AR = Androgen receptor. *significance at 5% level, ** significance at 1% level. The analysis are based on multipliers of staining intensity and fraction (nuclear score) for DACH2, RBM3, Chek1, Chek2 and MCM3 and categories of nuclear fraction for Ki67, AR, ER, and PR.