A) Peritoneal metastasis after intraperitoneal transplantation of FOC3 and MFOC3 | ||
---|---|---|
Cell Line | Number of Mice | Number of Mice with Metastasis (%) |
FOC3 | 10 | 0(0) |
MFOC3 | 16 | 13 (81.3) * |
*FOC3 vs MFOC3: p < 0.01 (χ2 test) | ||
B) Inhibition of Peritoneal metastasis in MFOC3 cells by anti-IL-1 β and anti- integrin β1 | ||
Antibody | Number of Mice | Number of Mice with Metastasis (%) |
control | 10 | 8 (80) a |
IL-1β | 10 | 7 (70) b |
Integrin β1 | 10 | 2 (20) c |
a vs b: non significant; | ||
a vs c: p < 0.01 (χ2 test) |