Skip to main content

Table 1 Peritoneal Metastasis and Inhibition

From: Production of IL1-beta by ovarian cancer cells induces mesothelial cell beta1-integrin expression facilitating peritoneal dissemination

A) Peritoneal metastasis after intraperitoneal transplantation of FOC3 and MFOC3
Cell Line Number of Mice Number of Mice with Metastasis (%)
FOC3 10 0(0)
MFOC3 16 13 (81.3) *
   *FOC3 vs MFOC3: p < 0.01 (χ2 test)
B) Inhibition of Peritoneal metastasis in MFOC3 cells by anti-IL-1 β and anti- integrin β1
Antibody Number of Mice Number of Mice with Metastasis (%)
control 10 8 (80) a
IL-1β 10 7 (70) b
Integrin β1 10 2 (20) c
   a vs b: non significant;
   a vs c: p < 0.01 (χ2 test)