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Table 5 Bootstrap multivariate HRs for baseline QoL measures

From: Longitudinal health-related quality of life assessment: implications for prognosis in ovarian cancer

Baseline variable

HR (BCa 95% CI)

P

General quality of life

  

Global

1.07 (0.93 – 1.24)

0.32

General function

  

Physical

1.07 (0.67 – 1.58)

0.65

Role

0.91(0.64 – 1.15)

0.42

Emotional

1.07 (0.71 – 1.53)

0.53

Cognitive

0.91 (0.65 – 1.13)

0.43

Social

1.02 (0.80 – 1.30)

0.80

General symptom

  

Fatigue

1.01 (0.75 – 1.73)

0.50

Nausea/vomiting

1.16 (0.64 – 1.59)

0.29

Pain

0.99 (0.69 – 1.23)

0.92

Dyspnea

1.10 (0.83 – 1.42)

0.39

Insomnia

0.90 (0.74 – 1.01)

0.15

Appetite loss

0.90 (0.64 – 1.08)

0.28

Constipation

0.94 (0.72 – 1.12)

0.43

Diarrhea

0.88 (0.58 – 1.11)

0.31

Financial

0.98 (0.75 – 1.20)

0.75

  1. • HRs correspond to a 10-point increment for QoL scores.
  2. • 2 sets of multivariate models were constructed: one for global QoL and other for all general function and symptom variables combined.
  3. • Multivariate model (for general function and symptom variables combined) adjusted for prior treatment history and all baseline QoL variables.
  4. • Multivariate model for global QoL adjusted for prior treatment history.