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Figure 3 | Journal of Ovarian Research

Figure 3

From: Serum agonistic autoantibodies against type-1 angiotensin II receptor titer in patients with epithelial ovarian cancer: a potential role in tumor cell migration and angiogenesis

Figure 3

Effect of AT 1 -AA on migration of OVCAR3 cells. AT1-AA increased migration in a dose-dependent manner (top panel). Relative to the control (A), cell migration by AT1-AA was significantly enhanced (B), which is comparable to the level found in Ang II (C). Enhancement of migration by AT1-AA was blocked either by AT1-AA-ECII (D) or losartan (E). Values are mean ± SE. n = 3 for each group. *p < 0.05 vs. saline control (Nor); †P < 0.05 vs. AT1-AA and Ang II. HPF = high power field (x 400).

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