Figure 6

Box plots of serum levels of A) FRA, C) MSLN and E) MPF in healthy controls and ovarian cancer patients by grade. Boxes indicate the 25th to 75th percentiles. The horizontal lines within the boxes are the median serum levels and the whiskers indicate the minimum and maximum values. P-values indicate statistical significance of differences between each group and healthy controls. ROC curves showing the performance of B) FRA, D) MSLN and F) MPF serum biomarkers in discrimination of healthy controls and ovarian cancer patients by grade (low, blue line; high, red line).