Figure 7

Box plots of serum levels of A) FRA, B) MSLN C) MPF D) CA125 and E) HE4 in healthy controls and serous ovarian cancer patients. Boxes indicate the 25th to 75th percentiles. The horizontal lines within the boxes are the median serum levels and the whiskers indicate the minimum and maximum values. P-values indicate statistical significance of differences between each group and healthy controls. F) ROC curves (FRA, blue line; MSLN, brown line; MPF, orange line; CA125, red line; HE4, green line) showing the performance of serum biomarkers in discrimination of healthy controls and serous ovarian cancer patients.