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Table 2 Biomarker serum levels with clinicopathological findings in ovarian cancer patients

From: Serum folate receptor alpha, mesothelin and megakaryocyte potentiating factor in ovarian cancer: association to disease stage and grade and comparison to CA125 and HE4

  

FRA (pg/mL)

MSLN (pg/mL)

MPF(pg/mL)

 

N (%)

Mean

Median

SD

Range

Mean

Median

SD

Range

Mean

Median

SD

Range

Normal

60 (19%)

341

324

122

176-696

11225

10300

4280

5169-26891

1869

1681

618

910-3691

Ovarian Cancer

258†(81%)

1680

549

5870

155-42523

43002

17279

61019

4274-311565

3602

2138

5994

717-72192

Histotype‡

             

Serous

215 (83%)

1616

586

3622

155-42523

48731

1681

62280

6322-311565

4275

2779

6446

717-72192

Endometrioid

22 (9%)

1862

434

5333

185-24843

38595

2138

64278

4274-240088

2786

1976

2887

1025-13492

Mucinous

15 (6%)

1047

497

2084

173-8475

20017

14632

19736

7672-88153

1875

1636

789

1071-4354

Stage

             

I

78 (30%)

1066

412

2876

162-24843

22654

14803

44258

4274-240088

2088

1686

1826

717-9075

II

47 (18%)

977

402

2877

164-8475

30439

15891

64662

6322-225597

2509

1807

3853

832-13492

III

45 (17%)

2014

775

5103

155-42523

58945

36112

69385

6370-257344

5887

3164

8499

858-72192

IV

45 (17%)

2811

1424

2477

241-14222

81160

19674

54307

8162-311565

4689

2196

5051

876-12882

Grade

             

Low

28 (11%)

541

449

409

185-2178

25615

14947

46648

4274-257344

2263

1904

1904

717-10850

High

148 (57%)

2090

653

4579

162-42523

55768

20225

67979

6322-311565

4589

2299

7255

741-72192

  1. †Represents multiple histologies (see Table 1).
  2. ‡There are too few samples of other histotypes for analysis.