From: External validation of anti-Müllerian hormone based prediction of live birth in assisted conception
Characteristic | Development cohort | Validation cohort | P |
---|---|---|---|
N = 381 | N = 822 | ||
Age (years) | 34.8 +/− 4.48 | 35.3 +/− 4.28 | Ns |
BMI (kg/m2) | 24 +/− 5.8 | 24.6 +/− 4.30 | <.05 |
AMH (ng/ml) | 1.3 (0.03, 13.8) | 2.16 (0.02, 38.6) | <.05 |
Duration of infertility (years) | 2.8 +/− 1.7 | 2.49 +/− 2.36 | <.05 |
Cause of infertility | |||
Combination of cause | 67 (17.5%) | 71 (8.6%) | <.05 |
Endometriosis | 45 (11.8%) | 39 (4.7%) | <.05 |
Idiopathic | 140 (36.8%) | 270 (32.8%) | Ns |
Male factor | 123 (32.4%) | 285 (34.7%) | Ns |
Ovulatory | 82 (21.5%) | 35 (4.3%) | <.05 |
Tubal disease | 57 (15.0%) | 122 (14.8%) | Ns |
Treatment outcomes: | |||
Duration of stimulation (days) | 12.8 +/− 2.8 | 10.4 +/− 2.11 | <.05 |
Dose (IU) | 205 +/− 58.6 | 216 +/− 59.0 | <.05 |
Oocytes per patient | 8.5 +/− 5.1 | 7.99 +/− 4.71 | Ns |
Embryo transfers performed | 347 (91.1%) | 713 (86.7%) | <.05 |
Number of embryos transferred: | |||
0 | 34 (9.8%) | 109 (13.3%) | Ns |
1 | 8 (2.3%) | 127 (15.5%) | <.05 |
2 | 83 (23.9%) | 534 (65.0%) | <.05 |
3 | 256 (73.8%) | 52 (6.3%) | <.05 |
Clinical pregnancy | 127 (33.3%) | 264 (32.1%) | Ns |
Live birth | 101 (26.5%) | 242 (29.4%) | Ns |