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Table 2 Summary of baseline characteristics and treatment outcomes for development and validation cohort

From: External validation of anti-Müllerian hormone based prediction of live birth in assisted conception

Characteristic

Development cohort

Validation cohort

P

N = 381

N = 822

Age (years)

34.8 +/− 4.48

35.3 +/− 4.28

Ns

BMI (kg/m2)

24 +/− 5.8

24.6 +/− 4.30

<.05

AMH (ng/ml)

1.3 (0.03, 13.8)

2.16 (0.02, 38.6)

<.05

Duration of infertility (years)

2.8 +/− 1.7

2.49 +/− 2.36

<.05

Cause of infertility

Combination of cause

67 (17.5%)

71 (8.6%)

<.05

Endometriosis

45 (11.8%)

39 (4.7%)

<.05

Idiopathic

140 (36.8%)

270 (32.8%)

Ns

Male factor

123 (32.4%)

285 (34.7%)

Ns

Ovulatory

82 (21.5%)

35 (4.3%)

<.05

Tubal disease

57 (15.0%)

122 (14.8%)

Ns

Treatment outcomes:

Duration of stimulation (days)

12.8 +/− 2.8

10.4 +/− 2.11

<.05

Dose (IU)

205 +/− 58.6

216 +/− 59.0

<.05

Oocytes per patient

8.5 +/− 5.1

7.99 +/− 4.71

Ns

Embryo transfers performed

347 (91.1%)

713 (86.7%)

<.05

Number of embryos transferred:

0

34 (9.8%)

109 (13.3%)

Ns

1

8 (2.3%)

127 (15.5%)

<.05

2

83 (23.9%)

534 (65.0%)

<.05

3

256 (73.8%)

52 (6.3%)

<.05

Clinical pregnancy

127 (33.3%)

264 (32.1%)

Ns

Live birth

101 (26.5%)

242 (29.4%)

Ns

  1. Values are presented as mean +/− SD, median (range) or n (%).
  2. Ns: non-significant.