Table 4 Sensitivity analysis to include only studies using allele-specific PCR as the genotyping method (2493 cases and 2764 controls)
From: mEH Tyr113His polymorphism and the risk of ovarian cancer development
Genotype comparison | OR [95% CI] | Z (P value) | Heterogeneity of study design | Analysis model | ||
|---|---|---|---|---|---|---|
χ 2 | df (P value) | I 2 | ||||
C-allele vs. T-allele | 1.09 [1.00, 1.18] | 1.91 (0.06) | 2.44 | 3 (0.49) | 0% | Fixed |
CC vs. TT | 1.21 [1.02, 1.43] | 2.22 (0.03) | 5.40 | 3 (0.14) | 44% | Fixed |
CC vs. TT + TC | 1.23 [1.03, 1.47] | 2.30 (0.02) | 3.62 | 3 (0.31) | 17% | Fixed |
TT vs. CC + TC | 0.94 [0.84, 1.05] | 1.07 (0.29) | 0.53 | 3 (0.91) | 0% | Fixed |