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Table 1 Clinical patient characteristics

From: Treatment reality in elderly patients with advanced ovarian cancer: a prospective analysis of the OVCAD consortium

 

Total (%) n = 275

Age < 70 years (%) n = 228

Age ≥ 70 years (%) n = 47

p value for group differences

Age (years)

   

<0.001a

Median

58

55

75

 

Range

18-85

18-69

70-85

 

FIGO stage

   

0.801c

IIB/C

15 (5.5)

13 (5.7)

2 (4.2)

 

IIIA/B

16 (5.8)

13 (5.7)

3 (6.4)

 

IIIC

196 (71.3)

165 (72.4)

31 (66.0)

 

IV

48 (17.5)

37 (16.2)

11 (23.4)

 

Nodal status

   

0.002b

pN0

65 (23.6)

58 (24.4)

7 (14.9)

 

pN1

143 (52.0)

124 (54.4)

19 (40.4)

 

Nx

67 (24.4)

46 (20.2)

21 (44.7)

 

Grading

   

0.907c

G1

10 (3.6)

9 (4.0)

1 (2.1)

 

G2

64 (23.4)

54 (23.8)

5 (21.3)

 

G3

200 (73.0)

164 (72.2)

42 (76.6)

 

Unknown

1

0

1

 

Histological subtype

   

0.700c

Serous

237 (86.2)

194 (85.1)

43 (91.5)

 

Mucinous

3 (1.1)

3 (1.3)

0 (0.0)

 

Other*

13 (4.7)

31 (13.6)

4 (8.5)

 

Presence of ascites

   

0.964b

None

66 (24.0)

54 (23.7)

12 (25.5)

 

<500 ml

101 (36.7)

84 (36.8)

17 (36.2)

 

>500 ml

108 (39.3)

90 (39.5)

18 (38.3)

 

Peritoneal carcinomatosis

   

0.513b

Yes

186 (67.4)

156 (68.0)

30 (63.8)

 

No

89 (32.4)

72 (32.0)

17 (36.2)

 

ECOG

   

0.047c

0

166 (60.4)

139 (61.0)

27 (57.5)

 

1

84 (30.6)

73 (32.0)

11 (23.4)

 

≥2

12 (4.4)

7 (3.1)

5 (10.6)

 

Unknown

13 (4.7)

9 (4.0)

4 (8.51)

 
  1. Overview of the clinical characteristics of all included patients with advanced ovarian cancer (n = 275). A total of 47 elderly patients ≥70 years are opposed to 228 patients younger than 70 years.
  2. a Man-Whitney-U-test, b Chi2-test, c Fisher’s exact test.
  3. * other = clear cell, endometroid, mixed cell, undifferentiated histology.
  4. FIGO International Federation of Gynecology and Obstetrics.
  5. ECOG Eastern Cooperative Oncology Group performance status.