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Table 4 Multivariate analysis of prognostic factors for elderly patients (≥70 years)

From: Treatment reality in elderly patients with advanced ovarian cancer: a prospective analysis of the OVCAD consortium

  Progression-free survival Overall survival
  HR 95% CI p value HR 95% CI p value
FIGO stage IV vs. II-IIIC 2.790 1.007 6.905 0.048 2.083 0.792 5.480 0.137
Grading         
G2 vs. G1 0.351 0.020 6.312 0.478 2.440 0.139 42.786 0.542
G3 vs. G1 2.023 0.144 28.437 0.601 5.165 0.368 72.453 0.223
Lymph-node status         
N1 vs. N0 0.277 0.050 1.532 0.141 0.191 0.260 1.404 0.104
Nx vs. N0 0.177 0.023 1.362 0.096 0.176 0.018 1.744 0.138
Residual tumor (yes vs. no) 0.635 0.233 1.734 0.376 0.919 0.321 2.634 0.876
Peritoneal carcinomatosis (yes vs. no) 1.752 0.734 4.183 0.207 0.563 0.612 3.317 0.490
Histologic subtype         
Serous vs. other 0.120 0.008 1.855 0.129 0.073 0.005 0.995 0.050
Chemotherapy         
Mono vs. combination 0.924 0.334 2.552 0.878 2.800 0.978 8.012 0.055
ECOG         
≥1 vs. 0 2.637 1.007 6.905 0.048 1.819 0.651 5.081 0.254
Unknown vs. 0 2.682 0.435 16.670 0.287 2.697 0.405 17.943 0.305
  1. Detailed analysis of possible prognostic factors regarding their statistical significance and independence by cox regression model for the cohort of patients age 70 and older (n = 47).