Treatment reality in elderly patients with advanced ovarian cancer: a prospective analysis of the OVCAD consortium

Table 4 Multivariate analysis of prognostic factors for elderly patients (≥70 years)

	Progression-free survival				Overall survival
	HR	95% CI		p value	HR	95% CI		p value
FIGO stage IV vs. II-IIIC	2.790	1.007	6.905	0.048	2.083	0.792	5.480	0.137
Grading
G2 vs. G1	0.351	0.020	6.312	0.478	2.440	0.139	42.786	0.542
G3 vs. G1	2.023	0.144	28.437	0.601	5.165	0.368	72.453	0.223
Lymph-node status
N1 vs. N0	0.277	0.050	1.532	0.141	0.191	0.260	1.404	0.104
Nx vs. N0	0.177	0.023	1.362	0.096	0.176	0.018	1.744	0.138
Residual tumor (yes vs. no)	0.635	0.233	1.734	0.376	0.919	0.321	2.634	0.876
Peritoneal carcinomatosis (yes vs. no)	1.752	0.734	4.183	0.207	0.563	0.612	3.317	0.490
Histologic subtype
Serous vs. other	0.120	0.008	1.855	0.129	0.073	0.005	0.995	0.050
Chemotherapy
Mono vs. combination	0.924	0.334	2.552	0.878	2.800	0.978	8.012	0.055
ECOG
≥1 vs. 0	2.637	1.007	6.905	0.048	1.819	0.651	5.081	0.254
Unknown vs. 0	2.682	0.435	16.670	0.287	2.697	0.405	17.943	0.305

Detailed analysis of possible prognostic factors regarding their statistical significance and independence by cox regression model for the cohort of patients age 70 and older (n = 47).

ISSN: 1757-2215