Figure 3

The miR-200c overexpression decreased tumor progression of CD44⁺ CD117⁺ CSCs in xenograft mice. A. 5 × 10⁴ CD44⁺CD117⁺CSCs transduced with lentivirus miR-200c or lentivirus-mock or without infection were subcutaneously injected in the nude mice ( n = 6/group). The figure shows the tumor growth dynamic state in the mice injected with the different CSCs (line, mean ± SE). B. Images of the tumor tissues dissected from the mice on day 56 after injection. C. Tumor-free mice on day 56 after injection(line, mean ± SE). *p < 0.01 and ** p < 0.01.