Figure 4

Impacts of the overexpression of miR-200c on ZEB1, E-Cadherin, and the Vimentin expressions in tumors, and tumor cell metastasis in mouse lungs. A-C. The qRT-PCR analysis results of the mRNA expression of ZEB1, Vimentin and E-Cadherin in the tumor tissues of EOC-bearing nude mice after injection with CD44⁺CD117⁺CSCs. D. The protein expression of ZEB1, E-Cadherin and Vimentin from the Western blotting analysis. E-G. The protein expression results from the gradation scanning analysis. H. The tumor metastasis in mouse lungs (stained in hematoxylin and eosin). I. The statistically significant differences are indicated by asterisk for **p < 0.01.