Centrosome amplification in ovarian cancer samples. The nine patient samples with the highest WDR62 expression and the nine samples with the lowest expression were subjected to immunohistochemistry against g-tubulin to identify centrosome. Samples with high expression (A), had a significantly higher percentage of cells with supernumerary centrosome than those with lower expression (B). The percentage of cells with more than two centrosomes seen in 200 consecutive cells in each group, with the mean, 25th and 75th quartiles, and minimum and maximum values. Original magnification, ×400 (high power).