Figure 5
From: Tracking NF-κB activity in tumor cells during ovarian cancer progression in a syngeneic mouse model
Elevation of M2 macrophage marker in tumor-bearing mice. QPCR analysis of the mRNA expression of the markers of (A) M2 macrophages, mannose-receptor (mann-R) and (B) M1 macrophages, CCL3, in RNA extracted from peritoneal lavages or ascites fluid. Values were normalized to corresponding levels of GAPDH mRNA expression and also CK18 mRNA levels, to account for epithelial content. The expression ratio of mann-R to CCL3 is shown in (C). Values are mean + SD for 3 mice per group. * p < 0.01 relative to non-injected mice, Mann-Whitney test.