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Figure 2 | Journal of Ovarian Research

Figure 2

From: PRIMA-1 increases cisplatin sensitivity in chemoresistant ovarian cancer cells with p53 mutation: a requirement for Akt down-regulation

Figure 2

The influence of different CDDP concentration on the PRIMA-induced apoptosis following Akt down-regulation. Apoptosis rate was analyzed with different concentration of CDDP (0–10 μM) plus PRIMA-1 (0 or 0.625 μM) which was strong enough to induce apoptosis in the combined treatment of CDDP in the absence (…….) and presence (_____) of DN-Akt. ### P<0.001, ## P<0.01; PRIMA-1+CDDP & DN-Akt vs. PRIMA-1 & CTL. Results are expressed as mean ± SEM of three independent experiments

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Journal of Ovarian Research

ISSN: 1757-2215

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