TY - JOUR AU - Chi, D. S. AU - Sabbatini, P. PY - 2000 DA - 2000// TI - Advanced ovarian cancer JO - Curr Treat Options Oncol VL - 1 UR - https://doi.org/10.1007/s11864-000-0058-1 DO - 10.1007/s11864-000-0058-1 ID - Chi2000 ER - TY - JOUR AU - Salom, E. AU - Almeida, Z. AU - Mirhashemi, R. PY - 2002 DA - 2002// TI - Management of recurrent ovarian cancer: evidence-based decisions JO - Curr Opin Oncol VL - 14 UR - https://doi.org/10.1097/00001622-200209000-00008 DO - 10.1097/00001622-200209000-00008 ID - Salom2002 ER - TY - JOUR AU - Burz, C. AU - Berindan-Neagoe, I. AU - Balacescu, O. AU - Irimie, A. PY - 2009 DA - 2009// TI - Apoptosis in cancer: key molecular signaling pathways and therapy targets JO - Acta Oncol VL - 48 UR - https://doi.org/10.1080/02841860902974175 DO - 10.1080/02841860902974175 ID - Burz2009 ER - TY - JOUR AU - Yip, K. W. AU - Reed, J. C. PY - 2008 DA - 2008// TI - Bcl-2 family proteins and cancer JO - Oncogene VL - 27 UR - https://doi.org/10.1038/onc.2008.307 DO - 10.1038/onc.2008.307 ID - Yip2008 ER - TY - JOUR AU - Youle, R. J. AU - Strasser, A. PY - 2008 DA - 2008// TI - The BCL-2 protein family: opposing activities that mediate cell death JO - Nat Rev Mol Cell Biol VL - 9 UR - https://doi.org/10.1038/nrm2308 DO - 10.1038/nrm2308 ID - Youle2008 ER - TY - JOUR AU - Chipuk, J. E. AU - Moldoveanu, T. AU - Llambi, F. AU - Parsons, M. J. AU - Green, D. R. PY - 2010 DA - 2010// TI - The BCL-2 family reunion JO - Mol Cell VL - 37 UR - https://doi.org/10.1016/j.molcel.2010.01.025 DO - 10.1016/j.molcel.2010.01.025 ID - Chipuk2010 ER - TY - JOUR AU - Frenzel, A. AU - Grespi, F. AU - Chmelewskij, W. AU - Villunger, A. PY - 2009 DA - 2009// TI - Bcl2 family proteins in carcinogenesis and the treatment of cancer JO - Apoptosis VL - 14 UR - https://doi.org/10.1007/s10495-008-0300-z DO - 10.1007/s10495-008-0300-z ID - Frenzel2009 ER - TY - JOUR AU - O’Kane, S. L. AU - Pound, R. J. AU - Campbell, A. AU - Chaudhuri, N. AU - Lind, M. J. AU - Cawkwell, L. PY - 2006 DA - 2006// TI - Expression of bcl-2 family members in malignant pleural mesothelioma JO - Acta Oncol VL - 45 UR - https://doi.org/10.1080/02841860500468927 DO - 10.1080/02841860500468927 ID - O’Kane2006 ER - TY - JOUR AU - Brotin, E. AU - Meryet-Figuière, M. AU - Simonin, K. AU - Duval, R. E. AU - Villedieu, M. AU - Leroy-Dudal, J. PY - 2010 DA - 2010// TI - Bcl-XL and MCL-1 constitute pertinent targets in ovarian carcinoma and their concomitant inhibition is sufficient to induce apoptosis JO - Int J Cancer VL - 126 ID - Brotin2010 ER - TY - JOUR AU - Wuilleme-Toumi, S. AU - Robillard, N. AU - Gomez, P. AU - Moreau, P. AU - Le, G. S. AU - Avet-Loiseau, H. PY - 2005 DA - 2005// TI - Mcl-1 is overexpressed in multiple myeloma and associated with relapse and shorter survival JO - Leukemia VL - 19 UR - https://doi.org/10.1038/sj.leu.2403784 DO - 10.1038/sj.leu.2403784 ID - Wuilleme-Toumi2005 ER - TY - JOUR AU - Lu, Y. AU - Zhang, X. D. AU - Lan, J. AU - Huang, G. AU - Varin, E. AU - Lincet, H. PY - 2011 DA - 2011// TI - Citrate induces apoptotic cell death: a promising Way for treating gastric carcinoma? JO - Anticancer Res VL - 31 ID - Lu2011 ER - TY - JOUR AU - Varin, E. AU - Denoyelle, C. AU - Brotin, E. AU - Meryet-Figuiere, M. AU - Giffard, F. AU - Abeilard, E. PY - 2010 DA - 2010// TI - Downregulation of Bcl-xL and Mcl-1 is sufficient to induce cell death in mesothelioma cells highly refractory to conventional chemotherapy JO - Carcinogenesis VL - 31 UR - https://doi.org/10.1093/carcin/bgq026 DO - 10.1093/carcin/bgq026 ID - Varin2010 ER - TY - JOUR AU - Simonin, K. AU - Brotin, E. AU - Dufort, S. AU - Dutoit, S. AU - Goux, D. AU - N’diaye, M. PY - 2009 DA - 2009// TI - Mcl-1 is an important determinant of the apoptotic response to the BH3-mimetic molecule HA14-1 in cisplatin-resistant ovarian carcinoma cells JO - Mol Cancer Ther VL - 8 UR - https://doi.org/10.1158/1535-7163.MCT-09-0493 DO - 10.1158/1535-7163.MCT-09-0493 ID - Simonin2009 ER - TY - JOUR AU - Lepleux, C. AU - Abeilard-Lemoisson, E. AU - Duval, M. AU - Icard, P. AU - Lincet, H. PY - 2012 DA - 2012// TI - siPGK1 Sensitizes chemoresistant human ovarian cancer cell lines to cisplatin JO - Anticancer Res VL - 32 ID - Lepleux2012 ER - TY - JOUR AU - Simonin, K. AU - N’diaye, M. AU - Lheureux, S. AU - Loussouarn, C. AU - Dutoit, S. AU - Briand, M. PY - 2013 DA - 2013// TI - Platinum compounds sensitize ovarian carcinoma cells to ABT-737 by modulation of the Mcl-1/Noxa axis JO - Apoptosis VL - 18 UR - https://doi.org/10.1007/s10495-012-0799-x DO - 10.1007/s10495-012-0799-x ID - Simonin2013 ER - TY - JOUR AU - Lincet, H. AU - Guével, B. AU - Pineau, C. AU - Allouche, S. AU - Lemoisson, E. AU - Poulain, L. PY - 2012 DA - 2012// TI - Comparative 2D-DIGE proteomic analysis of ovarian carcinoma cells: toward a reorientation of biosynthesis pathways associated with acquired platinum resistance JO - J Proteomics VL - 75 UR - https://doi.org/10.1016/j.jprot.2011.10.030 DO - 10.1016/j.jprot.2011.10.030 ID - Lincet2012 ER - TY - JOUR AU - Bertout, J. A. AU - Patel, S. A. AU - Simon, M. C. PY - 2008 DA - 2008// TI - The impact of O2 availability on human cancer JO - Nat Rev Cancer VL - 8 UR - https://doi.org/10.1038/nrc2540 DO - 10.1038/nrc2540 ID - Bertout2008 ER - TY - JOUR AU - Monti, E. AU - Gariboldi, M. B. PY - 2011 DA - 2011// TI - HIF-1 as a target for cancer chemotherapy, chemosensitization and chemoprevention JO - Curr Mol Pharmacol VL - 4 UR - https://doi.org/10.2174/1874467211104010062 DO - 10.2174/1874467211104010062 ID - Monti2011 ER - TY - JOUR AU - Vaupel, P. AU - Mayer, A. PY - 2007 DA - 2007// TI - Hypoxia in cancer: significance and impact on clinical outcome JO - Cancer Metastasis Rev VL - 26 UR - https://doi.org/10.1007/s10555-007-9055-1 DO - 10.1007/s10555-007-9055-1 ID - Vaupel2007 ER - TY - JOUR AU - Icard, P. AU - Lincet, H. PY - 1826 DA - 1826// TI - A global view of the biochemical pathways involved in the regulation of the metabolism of cancer cells JO - Biochim Biophys Acta VL - 2012 ID - Icard1826 ER - TY - JOUR AU - Icard, P. AU - Poulain, L. AU - Lincet, H. PY - 1825 DA - 1825// TI - Understanding the central role of citrate in the metabolism of cancer cells JO - Biochim Biophys Acta VL - 2012 ID - Icard1825 ER - TY - JOUR AU - Del GM, V. AU - Letai, A. PY - 2008 DA - 2008// TI - Rational design of therapeutics targeting the BCL-2 family: are some cancer cells primed for death but waiting for a final push? JO - Adv Exp Med Biol VL - 615 UR - https://doi.org/10.1007/978-1-4020-6554-5_8 DO - 10.1007/978-1-4020-6554-5_8 ID - Del GM2008 ER - TY - JOUR AU - Liu, J. R. AU - Fletcher, B. AU - Page, C. AU - Hu, C. AU - Nunez, G. AU - Baker, V. PY - 1998 DA - 1998// TI - Bcl-xL is expressed in ovarian carcinoma and modulates chemotherapy-induced apoptosis JO - Gynecol Oncol VL - 70 UR - https://doi.org/10.1006/gyno.1998.5125 DO - 10.1006/gyno.1998.5125 ID - Liu1998 ER - TY - JOUR AU - Tagscherer, K. E. AU - Fassl, A. AU - Campos, B. AU - Farhadi, M. AU - Kraemer, A. AU - Bock, B. C. PY - 2008 DA - 2008// TI - Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins JO - Oncogene VL - 27 UR - https://doi.org/10.1038/onc.2008.259 DO - 10.1038/onc.2008.259 ID - Tagscherer2008 ER - TY - JOUR AU - Kruspig, B. AU - Nilchian, A. AU - Orrenius, S. AU - Zhivotovsky, B. AU - Gogvadze, V. PY - 2012 DA - 2012// TI - Citrate kills tumor cells through activation of apical caspases JO - Cell Mol Life Sci VL - 69 UR - https://doi.org/10.1007/s00018-012-1166-3 DO - 10.1007/s00018-012-1166-3 ID - Kruspig2012 ER - TY - JOUR AU - Oltersdorf, T. AU - Elmore, S. W. AU - Shoemaker, A. R. AU - Armstrong, R. C. AU - Augeri, D. J. AU - Belli, B. A. PY - 2005 DA - 2005// TI - An inhibitor of Bcl-2 family proteins induces regression of solid tumours JO - Nature VL - 435 UR - https://doi.org/10.1038/nature03579 DO - 10.1038/nature03579 ID - Oltersdorf2005 ER - TY - JOUR AU - Ding, Q. AU - He, X. AU - Hsu, J. M. AU - Xia, W. AU - Chen, C. T. AU - Li, L. Y. PY - 2007 DA - 2007// TI - Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization JO - Mol Cell Biol VL - 27 UR - https://doi.org/10.1128/MCB.00620-06 DO - 10.1128/MCB.00620-06 ID - Ding2007 ER - TY - JOUR AU - Maurer, U. AU - Charvet, C. AU - Wagman, A. S. AU - Dejardin, E. AU - Green, D. R. PY - 2006 DA - 2006// TI - Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1 JO - Mol Cell VL - 21 UR - https://doi.org/10.1016/j.molcel.2006.02.009 DO - 10.1016/j.molcel.2006.02.009 ID - Maurer2006 ER - TY - JOUR AU - Nijhawan, D. AU - Fang, M. AU - Traer, E. AU - Zhong, Q. AU - Gao, W. AU - Du, F. PY - 2003 DA - 2003// TI - Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation JO - Genes Dev VL - 17 UR - https://doi.org/10.1101/gad.1093903 DO - 10.1101/gad.1093903 ID - Nijhawan2003 ER - TY - JOUR AU - Zhao, Y. AU - Altman, B. J. AU - Coloff, J. L. AU - Herman, C. E. AU - Jacobs, S. R. AU - Wieman, H. L. PY - 2007 DA - 2007// TI - Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1 JO - Mol Cell Biol VL - 27 UR - https://doi.org/10.1128/MCB.00153-07 DO - 10.1128/MCB.00153-07 ID - Zhao2007 ER - TY - JOUR AU - Poulain, L. AU - Lincet, H. AU - Duigou, F. AU - Deslandes, E. AU - Sichel, F. AU - Gauduchon, P. PY - 1998 DA - 1998// TI - Acquisition of chemoresistance in a human ovarian carcinoma cell is linked to a defect in cell cycle control JO - Int J Cancer VL - 78 UR - https://doi.org/3.0.CO;2-6 DO - 3.0.CO;2-6 ID - Poulain1998 ER - TY - JOUR AU - Michels, J. AU - O’Neill, J. W. AU - Dallman, C. L. AU - Mouzakiti, A. AU - Habens, F. AU - Brimmell, M. PY - 2004 DA - 2004// TI - Mcl-1 is required for Akata6 B-lymphoma cell survival and is converted to a cell death molecule by efficient caspase-mediated cleavage JO - Oncogene VL - 23 UR - https://doi.org/10.1038/sj.onc.1207648 DO - 10.1038/sj.onc.1207648 ID - Michels2004 ER - TY - JOUR AU - Han, J. AU - Goldstein, L. A. AU - Gastman, B. R. AU - Rabinowich, H. PY - 2006 DA - 2006// TI - Interrelated roles for Mcl-1 and BIM in regulation of TRAIL-mediated mitochondrial apoptosis JO - J Biol Chem VL - 281 UR - https://doi.org/10.1074/jbc.M510349200 DO - 10.1074/jbc.M510349200 ID - Han2006 ER - TY - CHAP AU - Kim, S. M. AU - Yun, M. R. AU - Hong, Y. K. AU - Solca, F. AU - Kim, J. H. AU - Kim, H. J. PY - 2013 DA - 2013// TI - Glycolysis inhibition sensitizes non-small cell lung cancer with T790M mutation to irreversible EGFR inhibitors via translational suppression of Mcl-1 by AMPK activation BT - Mol Cancer Ther ID - Kim2013 ER - TY - JOUR AU - Yi, C. H. AU - Pan, H. AU - Seebacher, J. AU - Jang, I. H. AU - Hyberts, S. G. AU - Hefffron, G. J. PY - 2011 DA - 2011// TI - Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival JO - Cell VL - 146 UR - https://doi.org/10.1016/j.cell.2011.06.050 DO - 10.1016/j.cell.2011.06.050 ID - Yi2011 ER -