Figure 1

Effect of citrate on two ovarian cancer cell lines: SKOV3 (A) and IGROV1-R10 (B). Evolution of viable cells up to 72 H after continuous exposure to 5, 10 and 20 mM of citrate (CT). Exponentially growing SKOV3 cells (A) or IGROV1-R10 cells (B) were treated with different citrate concentrations in the medium with SVF. The number of viable cells was assessed by the trypan blue exclusion test at various times after treatment. Results are expressed as the mean values of two independent experiments. Analysis of variance was used to determine significance. **: p < 0.05; ***: p < 0.001.