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Table 1 Chemosensitivity using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay

From: Establishment and characterization of a cell line (NOMH-1) originating from a human endometrioid adenocarcinoma of the ovary

Drug

EC50

PPC

 

(μg/mL)

(μg/mL)

ACD

>0.1

0.08

ADM

16.5

0.4

BLM

>1000

3.3

CBDCA

>300

37.1

CDDP

23.2

8.5

CPA

>10

4.3

CPT-11

1.79

0.05

5-FU

497

15.3

MMC

6.5

2.4

MTX

>300

3

PTX

5.1

11.8

VCR

15

0.1

VLB

16

0.15

VP-16

197

13

  1. EC50, effective concentration for 50% kill; PPC, peak plasma concentration taken intravenously; ACD, actinomycin D; ADM, doxorubicin; BLM, bleomycin; CBDCA, carboplatin; CDDP, cisplatin; CPA, 4-hydroperoxy-cyclophosphamide; CPT-11, irinotecan hydrochloride; 5-FU, 5-fluorouracil; MMC, mitomycin C; MTX, methotrexate; PTX, paclitaxel; VCR, vincristine; VLB, vinblastine; VP-16, etoposide;.
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Journal of Ovarian Research

ISSN: 1757-2215

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