Table 1 Results obtained after comparison of 5 combinations of fibrinogen and thrombin with in vitro culture of fibrin clots encapsulating human isolated ovarian stromal cells from four patients (numbered 1 to 4)
From: First step in developing a 3D biodegradable fibrin scaffold for an artificial ovary
Combination | Cell density | Density dynamics (%) mean ± SD | Proliferation index (%) mean ± SD | Apoptotic index (%) mean ± SD | |
|---|---|---|---|---|---|
Day 0 | Day 7 | ||||
F25/T4 | 0.0783 ± 0.0376 | 2.3038 ± 0.5988 | 96.46 ± 1.97 | 4.38 ± 4.81 | 26.99 ± 23.45 |
F50/T1 | 0.0524 ± 0.0113 | 1.8028 ± 1.1627 | 92.78 ± 9.79 | 1.35 ± 1.24 | 18.20 ± 14.94 |
F50/T20 | 0.0566 ± 0.0248 | 1.3848 ± 0.8639 | 86.89 ± 19.60 | 3.23 ± 2.66 | 18.50 ± 10.35 |
F12.5/T1 | 0.0757 ± 0.0148 | 1.6946 ± 0.2691 | 95.42 ± 1.28 | 4.45 ± 2.34 | 23.19 ± 35.11 |
F100/T4 | 0.0397 ± 0.0176 | 0.8243 ± 0.9104 | 58.29 ± 49.53 | 5.10 ± 3.40 | 3.77 ± 1.17 |