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Table 1 The KEGG pathway of the DEGs

From: RETRACTED ARTICLE: Investigation of the hub genes and related mechanism in ovarian cancer via bioinformatics analysis

Category KEGG pathway term Count Genes P-value
Up-regulated DEGs hsa00982 drug metabolism 8 CYP3A5, GSTM3, MAOA, … 0.004592
hsa05200 pathways in cancer 21 WNT5A, BMP2, FGF9, … 0.006931
hsa00980 metabolism of xenobiotics by cytochrome P450 7 AKR1C2, CYP3A5, GSTM3, … 0.015153
hsa00350 tyrosine metabolism 6 MAOA, ALDH1A3, AOX1, … 0.015606
hsa04610 complement and coagulation cascades 7 THBD, C3, CFH, TFPI, … 0.028328
hsa00330 arginine and proline metabolism 6 GATM, MAOA, GLS, MAOB, … 0.032382
hsa04510 focal adhesion 13 CAV2, CAV1, COL3A1, MET, … 0.038664
Down-regulated DEGs hsa04110 cell cycle 7 CCNE1, CDKN2A, CCNB2, … BUB1B, 1.06E-05
hsa04115 p53 signaling pathway 5 CCNE1, CDKN2A, CCNB2, … 1.78E-04
hsa05200 pathways in cancer 7 CCNE1, FGF18, CDKN2A, … 0.002121
hsa04114 oocyte meiosis 4 CCNE1, CCNB2, AURKA, … 0.011244