| GnRHa trigger plus intensive luteal steroid support (N = 363) | Conventional hCG trigger (N = 257) | p |
---|---|---|---|
Total FSH (IU) | 1,500 (1,300-1,800) | 1,650 (1,200-2,200) | 0.12 |
Peak Oestradiol (E2) (pg/ml) | 11,850 (8,700-15,395) | 8,598 (5,510-12,350) | 0.0001 |
LH on day of trigger (IU) | 1.95 (1.21-3.48) | 2.14 (1.28-3.49) | 0.46 |
Follicles >12 mm | 20 (17–25) | 18 (16–21) | 0.0001 |
Oocytes | 19 (15–24) | 18 (15–22) | 0.02 |
Embryos | 11 (7–15) | 10 (7–13) | 0.14 |
Embryo transfers (ET) (n,% of total cycles) | 322 (88.7%) | 213 (83%) | 0.038 |
Cancellations of ET due to early signs of OHSS (n,% of total cycles) | 2 (0.55%) | 22 (8.6%) | <0.0001 |
Embryos transferred | 3 | 3 | Â |
Positive pregnancy test (n,%per cycle) | 134 (36.9%) | 112 (43.5%) | 0.095 |
Clinical Pregnancy (n,%per cycle) | 109 (30%) | 77 (30%) | 0.99 |
Implantation rate (n,%) | 137/966 (14.2%) | 106/639 (16.6%) | 0.978 |
Miscarriages (n,% per cycle) | 5 (1.4%) | 15 (5.8%) | 0.002 |
Live birth rate (n,% per cycle) | 108 (29.8%) | 75 (29.2%) | 0.69 |
Multiple pregnancy rate (n,% of live-birth) | 28 (25.9%) | 29 (38.7%) | 0.067 |
OHSS cases (severe) (n,% per cycle) | 1 (0.3%) | 18 (7%) | <0.0001 |