Table 1 RNA sequencing shows significant differences in transcriptomes of the EEC16 and OSEC lines
From: Novel three-dimensional in vitro models of ovarian endometriosis
Gene symbol | Gene name | OSEC11 expression | EEC16 expression | Fold change | q-value |
|---|---|---|---|---|---|
Highly expressed in EEC16 | Â | Â | Â | Â | Â |
HAS1 | Hyaluronan synthase 1 | 0.19 | 148.84 | 777.83 | 0.00E + 00 |
NCAM1 | Neural cell adhesion molecule 1 | 0.02 | 11.33 | 524.29 | 3.44E-08 |
CHL1 | Cell adhesion molecule with homology to L1CAM | 0.06 | 29.64 | 491.01 | 0.00E + 00 |
KRT19 | Keratin 19 | 0.74 | 253.34 | 341.72 | 0.00E + 00 |
PAQR5,Y_RNA | Progestin and adipoQ receptor family member V | 0.34 | 101.55 | 301.90 | 3.07E-03 |
ODZ2 | Odz, odd Oz/ten-m homolog 2 (Drosophila) | 0.05 | 13.68 | 288.70 | 1.19E-06 |
FBLN2 | Fibulin2 | 0.44 | 108.01 | 246.49 | 4.84E-11 |
SLC24A3 | Solute carrier family 24 (sodium/potassium/calcium exchanger), member 31 | 0.02 | 4.47 | 244.08 | 4.34E-06 |
CDH20 | Cadherin 20, type 2 | 0.05 | 12.94 | 242.76 | 5.11E-07 |
MST1R | Macrophage stimulating 1 receptor (c-met-related tyrosine kinase) | 0.02 | 4.09 | 238.53 | 2.60E-03 |
SLITRK5 | SLIT and NTRK-like family, member 5 | 0.02 | 3.76 | 236.12 | 4.86E-06 |
KRT19P1 | Keratin 19 pseudogene 1 | 0.07 | 15.32 | 222.27 | 6.83E-06 |
CATSPER2 | Cation channel, sperm associated 2 | 0.01 | 2.39 | 172.42 | 1.99E-04 |
SLC35F3 | Solute carrier family 35, member F3 | 0.03 | 3.89 | 147.18 | 6.17E-03 |
CCDC85A | Coiled-coil domain containing 85A | 0.04 | 5.32 | 145.01 | 1.46E-03 |
ALDH1A2 | Aldehyde dehydrogenase 1 family, member A2 | 0.16 | 21.60 | 137.26 | 0.00E + 00 |
NOVA1 | Neuro-oncological ventral antigen 1 | 0.04 | 4.50 | 123.52 | 6.61E-09 |
NEBL | Nebulette, Actin-binding Z-disk protein | 0.22 | 26.32 | 122.11 | 3.89E-13 |
AC121334.1,KIF21A | Kinesin family member 21A | 7.08 | 804.71 | 113.71 | 6.09E-04 |
ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.02 | 2.17 | 107.18 | 6.71E-08 |
PMS2 | PMS2 postmeiotic segregation increased 2 (S. cerevisiae) | 4.99 | 524.34 | 105.00 | 1.84E-05 |
MMEL1 | Membrane metallo-endopeptidase-like 1 | 0.04 | 4.06 | 99.76 | 1.19E-02 |
SULT1E1 | Sulfotransferase family 1E, estrogen-preferring, member 1 | 0.19 | 18.17 | 94.01 | 2.70E-05 |
PTPRD | Protein tyrosine phosphatase, receptor type, D | 0.03 | 2.64 | 90.18 | 2.44E-03 |
FBN2 | Fibrillin 2 | 0.43 | 36.94 | 86.48 | 0.00E + 00 |
DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 3.47 | 281.89 | 81.34 | 0.00E + 00 |
DSC2 | Desmocollin 2 | 0.06 | 4.98 | 80.65 | 1.02E-09 |
CD7 | CD7 molecule, T-cell leukemia antigen | 0.78 | 62.57 | 80.60 | 1.34E-11 |
RSPO4 | R-spondin 4 | 0.03 | 2.29 | 78.55 | 1.92E-02 |
C3AR1 | Complement component 3a receptor 1 | 0.07 | 5.56 | 77.19 | 5.05E-05 |
Highly expressed in OSEC11 | Â | Â | Â | Â | Â |
H19,MIR675 | H19, imprinted maternally expressed transcript (non-protein coding); microRNA675 | 79.38 | 0 | NA | 8.04E-12 |
AR | Androgen receptor | 4.16 | 0 | NA | 2.46E-09 |
CALCR | Calcitonin receptor | 3.19 | 0 | NA | 3.37E-06 |
DCSTAMP | Dendrocyte expressed seven transmembrane protein | 3.55 | 0 | NA | 1.37E-04 |
REN | Renin | 113.02 | 0 | NA | 2.81E-04 |
MGP | Matrix Gla protein | 56.34 | 0 | NA | 3.77E-04 |
KISS1 | KiSS-1 metastasis-suppressor | 98.79 | 0 | NA | 9.30E-04 |
RP11-13 L2.4 | Â | 7.26 | 0 | NA | 1.21E-03 |
LEF1 | Lymphoid enhancer-binding factor 1 | 4.58 | 0 | NA | 1.46E-03 |
HOXC12 | Homeobox C12 | 9.19 | 0 | NA | 1.91E-03 |
DACH2 | Dachshund homolog 2 (Drosophila) | 2.62 | 0 | NA | 2.05E-03 |
LPL | Lipoprotein lipase | 0.88 | 0 | NA | 2.08E-03 |
WNT16 | Wingless-type MMTV integration site family, member 16 | 2 | 0 | NA | 2.60E-03 |
PPP1R14A | Protein phosphatase 1, regulatory (inhibitor) subunit 14A | 10.01 | 0 | NA | 6.06E-03 |
WFDC1 | WAP four-disulfide core domain 1 | 2.49 | 0 | NA | 6.57E-03 |
SOD3 | Superoxide dismutase 3, extracellular | 11.15 | 0 | NA | 6.65E-03 |
GSTM5 | Glutathione S-transferase mu 5 | 2.37 | 0 | NA | 8.57E-03 |
MKRN3 | Makorin ring finger protein 3 | 2.24 | 0 | NA | 9.50E-03 |
LINC00460 | Long intergenic non-protein coding RNA 460 | 3.24 | 0 | NA | 9.83E-03 |
C8orf4 | Chromosome 8 open reading frame 4 | 6.8 | 0 | NA | 1.20E-02 |
PPAPDC3 | Phosphatidic acid phosphatase type 2 domain containing 3 | 3.84 | 0 | NA | 1.27E-02 |
LYPD1 | LY6/PLAUR domain containing 1 | 4.58 | 0 | NA | 1.50E-02 |
RCSD1, RP3-455 J7.4 | RCSD domain containing 1 | 1.64 | 0 | NA | 1.51E-02 |
ITIH3 | Inter-alpha-trypsin inhibitor heavy chain 3 | 2.11 | 0 | NA | 1.59E-02 |
MAOB | Monoamine oxidase B | 1.13 | 0 | NA | 1.69E-02 |
HOXC11 | Homeobox C11 | 1.68 | 0 | NA | 1.78E-02 |
ITPRIPL1 | Inositol 1,4,5-trisphosphate receptor interacting protein-like 1 | 1.21 | 0 | NA | 1.96E-02 |
CD36 | CD36 molecule (thrombospondin receptor) | 1.88 | 0 | NA | 2.26E-02 |
KIAA1456 | KIAA1456 | 1.59 | 0 | NA | 2.28E-02 |
IQGAP2 | IQ motif containing GTPase activating protein 2 | 1.24 | 0 | NA | 2.46E-02 |