Table 4 Multivariate Cox regression analysis of clinical, pathological, and TAM-related prognostic factors for ovarian cancer*

Age

0.234

 < 40

1 (reference)

-

 40 - 49

1.016

(0.205, 4.931)

 50 - 59

1.664

(0.386, 7.181)

 60 - 69

1.239

(0.292, 5.253)

 ≥ 70

0.329

(0.043, 2.492)

Gravidity

0.726

 0 - 1

1 (reference)

-

 2 - 3

1.000

(0.424, 2.355)

 4 - 5

0.904

(0.345, 2.367)

 ≥ 5

0.612

(0.184, 2.031)

Parity

0.851

 0 - 1

1 (reference)

-

 2 - 3

1.068

(0.536, 2.129)

Menopause

0.944

 Yes

1 (reference)

-

 No

0.969

(0.407, 2.304)

Ascites

0.120

 Yes

1 (reference)

-

 No

0.421

(0.142, 1.252)

Peritoneal metastasis

<0.001^#

 Yes

1 (reference)

-

 No

10.753

(3.768, 30.685)

Lymphatic metastasis

0.678

 Yes

1 (reference)

-

 No

0.814

(0.307, 2.156)

Stage

<0.001^#

 I

1 (reference)

-

 II

3.5

(0.781, 15.677)

 III

6.1

(1.733, 21.469)

 IV

38.5

(7.377, 200.926)

Histotype

0.003^#

 Serous

1 (reference)

-

 Mucinous

0.119

(0.017, 0.855)

 Endometrioid

0.560

(0.116, 2.707)

 Clear cell

0.780

(0.146, 4.159)

 Undifferentiated

5.952

(1.339, 26.451)

Grade

0.002^#

 G1

1 (reference)

-

 G2

4.557

(2.373, 8.753)

 G3

8.197

(2.456, 27.362)

Size of residual site

0.008^#

 < 2 cm

1 (reference)

-

 ≥ 2 cm

2.786

(1.307, 5.937)

Overall M1/M2 TAM ratio

0.013^#

 < 1.371

1 (reference)

-

 ≥ 1.371

0.448

(0.238, 0.842)