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Table 1 Fold change in gene expression comparing control (untreated cells) and 10 ng/ml IT treated B76 cells

From: The MOC31PE immunotoxin reduces cell migration and induces gene expression and cell death in ovarian cancer cells

Cancer pathway Gene Description Fold change
Adhesion ITGα3 Integrin α3 -2.1
Angiogenesis FGFR2 Fibroblast growth factor receptor 2 2.1
IFNβ1 Interferon β 3.8
TNF Tumor necrosis factor 3.8
IL8 Interleukin 8 5.0
THBS1 Thrombospondin 5.8
PDGFβ Platelet derived growth factor β 9.0
Cell cycle control and DNA damage repair CDC25A CDC25 phosphatase family 2.4
CDKN1A Cyclin dependent kinase inhibitor 2.4
Signal transduction molecules and transcription factors ERBB2 Epidermal growth factor receptor family -2.9
ETS2 Transcription factor 3.2
NFκβ1 Transcription factor 3.2
JUN Transcription factor 5.4
  1. Results from two independent experiments are analysed together.