Table 1 Fold change in gene expression comparing control (untreated cells) and 10 ng/ml IT treated B76 cells
Cancer pathway | Gene | Description | Fold change |
|---|---|---|---|
Adhesion | ITGα3 | Integrin α3 | -2.1 |
Angiogenesis | FGFR2 | Fibroblast growth factor receptor 2 | 2.1 |
IFNβ1 | Interferon β | 3.8 | |
TNF | Tumor necrosis factor | 3.8 | |
IL8 | Interleukin 8 | 5.0 | |
THBS1 | Thrombospondin | 5.8 | |
PDGFβ | Platelet derived growth factor β | 9.0 | |
Cell cycle control and DNA damage repair | CDC25A | CDC25 phosphatase family | 2.4 |
CDKN1A | Cyclin dependent kinase inhibitor | 2.4 | |
Signal transduction molecules and transcription factors | ERBB2 | Epidermal growth factor receptor family | -2.9 |
ETS2 | Transcription factor | 3.2 | |
NFκβ1 | Transcription factor | 3.2 | |
JUN | Transcription factor | 5.4 |